在内镜检查中,阻塞性食道癌与降低生存率和糟糕的结果有关
Shaul Pery1, Fadi Abu Baker1, Yael Kopelman1
1Department of Gastroenterology and Hepatology, Hillel Yaffe Medical Center, Hadera, Israel, Rappaport Faculty of Medicine, Technion-Institute of Technology, Haifa, Israel.
The Israel Medical Association journal : IMAJ
|May 28, 2023
概括
患有阻光线的瘤的食道癌症患者的中位生存时间比那些没有阻瘤的患者要短得多. 这种阻塞与食道癌的晚期转移性阶段没有相关性.
科学领域:
- 胃肠道学和瘤学
- 临床内镜检查 临床内镜检查
- 癌症预后 癌症预后
背景情况:
- 食道癌是癌症死亡的主要原因,包括腺癌和状细胞癌.
- 诊断时内镜检测出遮光质的发现缺乏明确的预后意义.
- 研究食道癌症内镜阻塞的预后价值至关重要.
研究的目的:
- 为了确定食道病变阻塞的内镜发现是否会影响患者的预后.
- 调查食道癌中光阻瘤的预后价值.
主要方法:
- 从2000年到2020年对上部胃肠道内镜研究的回顾性分析.
- 综合存活率,疾病阶段,组织学和阻塞性和非阻塞性食道瘤之间的位置的比较.
- 对瘤组之间的差异的统计评估.
主要成果:
- 在69名患者中,46%患有阻塞性和54%患有非阻塞性食道癌.
- 阻塞性病变 (3.5个月) 与非阻塞性病变 (10个月;P=0.001) 的中位生存时间明显较短.
- 在阻塞性和非阻塞性组之间,晚期 (第四阶段) 疾病百分比没有显著差异 (34.3%与37.8%;P=0.80).
结论:
- 在食道癌中,内镜证据表明膜阻塞预测了较差的中位数整体存活率.
- 瘤阻塞与食道癌转移阶段没有相关性.
- 由于预后较差,阻塞性食道瘤需要更密切的监测.
相关概念视频
Barrett Esophagus-I: Introduction
143
Barrett's esophagus is a medical condition where the esophageal mucosa is significantly damaged by stomach acid or other digestive fluids, often due to long-term exposure associated with gastroesophageal reflux disease (GERD). In GERD, a weakened or abnormally relaxed lower esophageal sphincter allows stomach acid to flow persistently into the esophagus.
This constant acid exposure transforms the esophagus's pink mucosal lining (stratified squamous epithelium) into a type of lining more...
This constant acid exposure transforms the esophagus's pink mucosal lining (stratified squamous epithelium) into a type of lining more...
143
Barrett Esophagus-II: Clinical Manifestations and Management
221
Individuals with Barrett's esophagus are often asymptomatic, but they may experience symptoms commonly associated with GERD, such as heartburn and acid regurgitation. Additional symptoms can include difficulty swallowing, chest pain, unintentional weight loss, blood in the stool (which may appear black, tarry, or bloody), and episodes of vomiting.
To diagnose Barrett's esophagus, healthcare providers often recommend an endoscopy for those showing symptoms of acid reflux. The procedure...
To diagnose Barrett's esophagus, healthcare providers often recommend an endoscopy for those showing symptoms of acid reflux. The procedure...
221
Esophageal Strictures-II: Clinical Features and Management
116
Patients with esophageal strictures often experience a range of symptoms. Initially, they may have difficulty swallowing solid foods, which can progress to include liquids. Additional symptoms may involve chest pain or discomfort, regurgitating food and fluids, heartburn, unintentional weight loss, coughing or choking during meals, and hoarseness.
Healthcare providers should gather a comprehensive medical history and conduct a physical examination for diagnosis. If esophageal stricture is...
Healthcare providers should gather a comprehensive medical history and conduct a physical examination for diagnosis. If esophageal stricture is...
116
Esophageal Strictures-I: Introduction
183
Esophageal strictures involve abnormal narrowing or tightening of the esophagus. They vary in length and severity, ranging from mild constriction to complete obstruction, and are classified as benign (noncancerous) or malignant (cancerous).
Etiology
The primary cause of esophageal strictures is long-standing gastroesophageal reflux disease (GERD), accounting for about 70 to 80% of adult cases. Chronic acid reflux can lead to injury and scarring of the esophageal lining, culminating in...
Etiology
The primary cause of esophageal strictures is long-standing gastroesophageal reflux disease (GERD), accounting for about 70 to 80% of adult cases. Chronic acid reflux can lead to injury and scarring of the esophageal lining, culminating in...
183
Endoscopic Procedures I: Esophagogastroduodenoscopy
231
An Esophagogastroduodenoscopy (EGD) is a diagnostic procedure in which an endoscopist uses a flexible, lighted endoscope to visualize the upper gastrointestinal (GI) tract. The procedure includes visualizing the oropharynx, esophagus, stomach, and the first part of the small intestine, the duodenum.
During an EGD, the endoscope can be used to:
During an EGD, the endoscope can be used to:
231
Esophageal Varices-II: Clinical Features and Management
102
Esophageal varices often manifest as gastrointestinal bleeding episodes, presenting symptoms like hematemesis (vomiting of blood), hematochezia (passing fresh blood via the rectum), and melena (black, tarry stools). Other signs can include weight loss, anorexia, abdominal discomfort, jaundice, pruritus, altered mental status, and muscle cramps.
In the initial assessment, a thorough review of the patient's medical history is vital to identify risk factors such as liver disease, alcohol...
In the initial assessment, a thorough review of the patient's medical history is vital to identify risk factors such as liver disease, alcohol...
102


