瓦克里强化了KampillakadiTaila的伤口愈合潜力
Pranjali P Dhawal1, Milind Gharpure2, Minal S Joshi3
1Animal Biotechnology and Biochemistry Division, Kelkar Education Trust's Scientific Research Centre, V. G. Vaze College Campus, Mithagar Road, Mulund East, Mumbai, Maharashtra, 400081, India.
Journal of Ayurveda and integrative medicine
|May 28, 2023
概括
这项研究表明,Wagatea spicata强化Kampillakadi Taila草本专有配方 (VKHPF) 有助于伤口愈合. VKHPF表现出显著的体外细胞增殖,抗氧化和抗菌活性,表明其在现代医学中的潜力.
科学领域:
- 植物化学 植物化学
- 皮肤病学 皮肤病学
- 药理学 药理学是指药理学的学科.
背景情况:
- 传统的印度医学使用Kampillakadi Taila治疗伤口.
- 这项研究研究了一种来自Kampillakadi Taila和Wagatea spicata根提取物的新草药配方 (VKHPF).
研究的目的:
- 为了化学分析VKHPF.
- 为了评估其抗氧化,抗微生物和体外伤口愈合特性.
主要方法:
- 使用GC-FAME和GC-HRMS进行化学表征.
- 在体外测试包括细胞增殖,测试,DPPH测试和时间杀死测试在NIH/3T3纤维细胞上进行.
主要成果:
- 在VKHPF中含有丰富的脂肪酸 (例如,油酸) 和维生素 (例如,托科菲醇).
- 它显著增强了细胞活力 (164%) 和增殖 (64%),实现了98%的伤口关闭,并表现出抗氧化剂 (IC50: 3.5 mg/ml) 和抗菌活性对S. aureus和P. aeruginosa.
结论:
- 这是第一个证明VKHPF的体外伤口愈合潜力的研究.
- 这些发现表明VKHPF可能是现代伤口护理疗法的宝贵补充.
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