发生率,特征,和怀孕的母亲的结果与子宫脱落
Rasika R Deshpande1, Shinya Matsuzaki2, Kaily R Cox1
1Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, University of Southern California, Los Angeles, CA (Drs Deshpande and Cox, Ms Foy, and Drs Mandelbaum and Matsuo).
American journal of obstetrics & gynecology MFM
|May 28, 2023
概括
孕妇子宫脱落,一种罕见的妊娠并发症,与增加孕妇和分娩不良结果的风险有关. 这项研究强调了与这种疾病相关的关键风险因素和并发症.
科学领域:
- 产科和妇科 产科和妇科
- 孕产妇和胎儿医学 孕产妇和胎儿医学
- 生殖健康 生殖健康
背景情况:
- 孕妇子宫 (GUP) 是怀孕期间子宫的异常下降,是一种罕见的并发症,其特征和结果不明.
- 现有的文献缺乏关于国家发病率和与GUP相关的孕产妇结果的全面数据.
研究的目的:
- 为了确定妊娠子宫落的全国发病率.
- 为了确定与GUP相关的患者和怀孕特征.
- 评估由GUP复杂的怀孕中母亲和分娩的结果.
主要方法:
- 从2016年1月到2019年12月使用国家住院患者样本 (NIS) 进行的回顾性队列研究.
- 包括14,647,670例分娩,暴露量以子宫缩的诊断来定义.
- 应用治疗权重的逆概率 (IPTW) 来调整混因素,然后进行多变量分析.
主要成果:
- 在每10万分娩中,GUP的发病率为23.8例 (4209例中的1例).
- 风险因素包括母亲的晚年,特定的种族/种族群体,吸烟,祖父多夫多妻制以及怀孕损失史.
- 与怀孕相关的并发症包括子宫缺陷,早产和子宫膜早产早破.
- 不良分娩结果包括早产早产,产后出血,子宫缩,子宫逆转,休克,输血产品和子宫切除术的增加率.
- 患有GUP的患者不太可能接受剖腹产.
结论:
- 孕妇子宫脱落是一个不常见的情况.
- GUP与更高的不良怀孕,分娩和产后并发症风险有关.
- 这一全国性的分析强调了需要提高对GUP的认识和管理策略.
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