来自Althaea officinalis Linn. 的多糖的分离,结构性质和生物活性. : 一个回顾: 一个回顾
Taotao Xue1, Kaihua Ruan2, Zhishu Tang3
1Co-construction Collaborative Innovation Center for Chinese Medicine Resources Industrialization by Shaanxi & Education Ministry, State Key Laboratory of Research & Development of Characteristic Qin Medicine Resources (Cultivation), Shaanxi University of Chinese Medicine, 712083 Xianyang, PR China.
International journal of biological macromolecules
|May 28, 2023
概括
Marshmallow 根中的 Althaea officinalis 多糖 (AOP) 提供了多种不同的药用益处. 本综述详细介绍了AOP提取,结构和药物发现和功能性食品的治疗潜力.
科学领域:
- 药理学 药理学是指药理学的学科.
- 植物化学 植物化学
- 自然产品化学 自然产品化学
背景情况:
- 阿尔泰亚官员林尼斯. (AO),被称为马什梅罗,是一种植物,在传统医学和食品中具有广泛的历史用途.
- 阿尔泰亚 officinalis 多糖 (AOP) 是AO的关键生物活性成分,具有广泛的药理活性.
- 现有的研究集中在AOP的各个方面,但缺乏全面的审查.
研究的目的:
- 系统地审查从Althaea officinalis的不同部位提取和净化AOP的方法.
- 总结AOP的化学结构,生物活动和结构-活动关系的特征.
- 探索AOP的当前应用,并提出治疗和功能性食品用途的未来研究方向.
主要方法:
- 关于Althaea officinalis多糖 (AOP) 提取,净化,表征和应用的主要研究的文献搜索.
- 对AOP的化学结构和生物活动的数据进行系统审查和综合.
- 分析结构-活动关系和当前的研究差距.
主要成果:
- 从AO种子,根,叶子和花中采用了多种不同的提取和净化技术来获得AOP.
- AOP显示出显著的抗咳,抗氧化,抗菌,抗癌,伤口愈合,免疫调节和不孕症治疗作用.
- 结构-活性关系研究对于了解AOP的生物活性和优化其治疗潜力至关重要.
结论:
- 阿尔泰亚 officinalis 多糖 (AOP) 是一个有前途的生物活性化合物,具有广泛的治疗潜力.
- 需要进一步的研究来解决目前的局限性,并充分利用AOP用于药物发现和功能性食品开发.
- 作为治疗剂和功能性食品成分,AOP具有显著的前景.
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