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老年人增强认知训练研究 (ACT) 的主要结果:一项tDCS和认知训练随机临床试验

Hanna K Hausman¹, Gene E Alexander², Ronald Cohen¹

¹Center for Cognitive Aging and Memory, McKnight Brain Institute, University of Florida, Gainesville, FL, USA; Department of Clinical and Health Psychology, College of Public Health and Health Professions, University of Florida, Gainesville, FL, USA.

Brain stimulation

|May 28, 2023

概括

将认知训练与跨直流刺激 (tDCS) 结合起来,并没有改善老年人的认知功能. 虽然单独的认知训练显示出好处,但在ACT试验中,添加tDCS并没有增强这些收益.

科学领域:

神经科学是一个神经科学.
老年学是指老年学的学科.
认知心理学认知心理学

背景情况:

老年人认知能力下降需要有效的干预措施.
认知训练在改善未经训练的任务和日常运作方面显示出不同的结果.
将认知训练与跨直流刺激 (tDCS) 结合起来可能会增强认知训练效果,但需要进行大规模测试.

研究的目的:

介绍来自"在老年人中增强认知训练 (ACT) "临床试验的主要发现.
为了测试积极的tDCS与认知训练相结合的假设,与假冒刺激相比,在流体认知方面取得了更大的改善.
在老年人中评估综合认知训练和tDCS的疗效.

主要方法:

379名老年人被随机分配;334人被纳入12周干预的治疗意图分析.
参与者每天接受认知训练,使用主动或假的tDCS两周,然后每周一次,持续10周.
回归模型评估了NIH工具箱流体认知复合分数在干预后和一年后的变化,控制共变量.

主要成果:

干预后立即观察到流体认知复合分数的改善,并在整个样本中进行一年的随访.
在任何时间点,在活跃的tDCS和虚假组之间都没有发现认知改善的显著差异.
该研究表明,在一个大队伍中,联合认知训练和tDCS的管理是可行的.

结论:

该ACT研究成功模拟了老年人联合tDCS和认知训练的管理.
虽然单独的认知训练可能会带来好处,但活跃的tDCS在本试验中没有提供添加优势.
进一步的分析将探索额外的认知,功能,情绪和神经标志物,以充分评估干预的有效性.

关键词:

认知认知是一种认知.认知训练是一种认知训练.干预干预干预年龄较大的成年人.tDCSCS 是一个很好的方法.

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