相关实验视频

Updated: Jul 28, 2025

Author Spotlight: Insights into an Efficient Murine Maxillary Orthodontic Model Protocol

Author Spotlight: Insights into an Efficient Murine Maxillary Orthodontic Model Protocol

Published on: October 27, 2023

发生在部的表皮炎性肌纤维细胞肉瘤:首次报告的部病例

Vivek Nayyar¹, Ongkila Bhutia², Aanchal Kakkar³

¹Department of Oral Pathology and Microbiology, Centre for Dental Education and Research, All India Institute of Medical Sciences, New Delhi, India.

Oral surgery, oral medicine, oral pathology and oral radiology

|May 28, 2023

概括

皮质炎症性肌纤维细胞肉瘤 (EIMS),一种通常在腹部发现的罕见瘤,在这里报告了一名32岁男性的上部. 这个案例标志着在这个解剖位置的EIMS的第一个记录实例.

科学领域:

在瘤学瘤学.
病理学病理学病理学
放射学放射学是一门学科.

背景情况:

皮质炎症性肌纤维细胞肉瘤 (EIMS) 是一种罕见的瘤实体,是炎症性肌纤维细胞瘤的亚型.
EIMS主要发生在腹部内部,其他解剖部位的报道有限.

研究的目的:

报告第一个已知发生在部的EIMS病例.
描述上性EIMS的临床,放射和组织病理特征.
讨论这种罕见瘤的诊断挑战和免疫类型特征.

主要方法:

一个32岁的男性患有上瘤的案例介绍.
放射性评估,包括CT扫描,以评估病变特征.
组织病理学检查和免疫组织化学分析 (ALK-1,SMA,panCK,EMA,CD30,desmin,CD34,STAT6,p53,INI-1,Ki-67) 进行.

主要成果:

放射学显示,右大骨有一个单独的,不规则的骨解病变,带有皮质侵蚀.
组织病理学揭示了一种瘤,其中包括螺旋状和上皮状细胞,状变化,缩和高线粒活动.
免疫组织化学证实瘤细胞对ALK-1,SMA,panCK,EMA呈阳性,对CD30,desmin,CD34,STAT6呈阴性,具有保留的INI-1和野生型p53. 基-67是22%. 这是22%.

结论:

这是第一个在部出现的EIMS报告的病例.
maksillary EIMS呈现为一种骨解性病变,具有明显的遗传病理和免疫类型特征.
早期诊断和适当的治疗对于管理这种罕见的恶性瘤至关重要.

更多相关视频

Author Spotlight: Unlocking the Mysteries of Oral Potential Malignancies

Author Spotlight: Unlocking the Mysteries of Oral Potential Malignancies

Published on: August 11, 2023

Induction of Mesenchymal-Epithelial Transitions in Sarcoma Cells

Induction of Mesenchymal-Epithelial Transitions in Sarcoma Cells

Published on: April 7, 2017

相关概念视频

Classification of Epithelial Tissues: Simple Epithelium

Classification of Epithelial Tissues: Simple Epithelium

Simple epithelium consists of a single layer of cells that lines body cavities and blood vessels. The shape of the cells in the epithelium reflects the function of the tissue. Cells in simple squamous epithelium appear as thin scales with flat, elliptical nuclei that mirror the form of the cell.
Because of the thinness of the cells, simple squamous epithelium is present where the rapid passage of chemical compounds is observed. For example, the endothelium that lines the capillaries and vessels...

Mesenchymal Stem Cells

Mesenchymal Stem Cells

Mesenchymal stem cells (MSCs) are adult stem cells that can differentiate into most connective tissue cell types, except for hematopoietic cells, depending upon the source of MSCs. For example, bone-marrow-derived MSCs (BM-MSCs) can differentiate into osteocytes, hepatocytes, and pancreatic and neuronal cells. MSCs can be isolated from various sources such as bone marrow, placenta, adipose tissue, teeth, and Wharton’s jelly, a gelatinous substance in the umbilical cord. The ease of their...