实现潜伏手术的目标能力:对膀外缩患者的累积事件分析
Preeya Khandge1, Christian C Morrill1, Wayland J Wu1
1James Buchanan Brady Urological Institute, Division of Pediatric Urology, Douglas A. Canning MD Exstrophy Database Center, Charlotte Bloomberg Children's Hospital, The Johns Hopkins Medical Institutions, Baltimore, MD, USA.
Journal of pediatric urology
|May 28, 2023
概括
大多数患有经典膀外缩 (CBE) 的患者在5.73岁时达到足够的膀容量以进行尿手术,这有助于在尿方面做出手术决策.
科学领域:
- 儿科泌尿外科 儿科泌尿外科
- 手术瘤学手术瘤学
- 重建性手术是一种重建性手术.
背景情况:
- 建立尿失禁是经典膀外缩 (CBE) 关闭后的一个关键里程碑.
- 足够的膀容量 (≥100 cc) 对于选择适当的失禁手术至关重要,例如膀部重建 (BNR) 或增强囊膜成形 (AC) 的大陆口腔.
研究的目的:
- 确定CBE患者达到BNR资格的膀容量的门年龄.
- 假设大多数患者在7岁时达到足够的膀容量,当考虑体手术时.
主要方法:
- 追溯对1388名外缩症患者的审查,其中253人满足了初级膀关闭后CBE的纳入标准.
- 膀容量通过重力囊泡测量;数据分析使用描述性统计和累积事件分析.
- 根据关闭位置,时间 (新生儿 vs 延迟) 和骨切除术状态分层的队列.
主要成果:
- 64.9%的患者达到目标膀容量 (≥100cc).
- 达到目标能力的中位时间为5.73年 (50%的概率).
- 关闭位置对达到目标能力的时间产生了重大影响 (作者机构:5.20年与医院外:6.26年).
结论:
- 这些发现有助于外科医生为家庭提供咨询,以了解在不同年龄段达到足够膀容量的可能性.
- 有助于描述在五岁时未达到100cc的人群中需要大陆口腔与膀增大.
- 支持实现尿失禁的有信息的手术规划,超过一半的患者达到各种手术选择的容量值.
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