对良性大气道狭窄的喷雾冷疗法:安全性和实践模式的多中心回顾性队列研究
Ankush P Ratwani1, Robert J Lentz1, Heidi Chen2
1Division of Allergy, Pulmonary, and Critical Care Medicine, Department of Internal Medicine, Vanderbilt University Medical Center.
Journal of bronchology & interventional pulmonology
|May 29, 2023
概括
对良性气道狭窄症 (BAS) 的喷雾冷疗法 (SCT) 在多中心研究中显示出低并发症率. 然而,在SCT应用中观察到实践的差异,突出了在BAS的这种辅助治疗中需要标准化的领域.
科学领域:
- 肺部医学 肺部医学
- 干预性肺病学 干预性肺病学
- 医疗器械 医疗器械
背景情况:
- 良性气道狭窄 (BAS) 造成了重大的临床和经济负担.
- 喷雾冷疗法 (SCT) 是一种建议的辅助疗法,以减少BAS复发.
- 最新的SCT系统的安全性和BAS的实践变化需要审查.
研究的目的:
- 评估最新的喷雾冷疗法 (SCT) 系统对良性气道狭窄 (BAS) 的安全性.
- 为了确定SCT在BAS治疗中的应用实践变化.
主要方法:
- 在七个学术机构进行了一项回顾性多中心队列研究.
- 分析了从102名患者获得的数据,这些患者在2013年至2022年期间接受了165次SCT手术.
- 人口统计数据,程序细节和不良事件从机构数据库和电子健康记录中提取.
主要成果:
- 最常见的BAS原因是阳性 (35%).
- 在其他标准干预措施 (75%) 之前,SCT经常被使用.
- 发生了四例肺胸病 (两例需要干预),并发现了一例短暂的低氧化症. 没有观察到气栓塞,血液动力学损害或死亡率.
结论:
- 对良性气道狭窄症 (BAS) 的辅助喷雾冷疗法 (SCT) 在这个队列中显示出较低的并发症率.
- 在SCT程序参数中存在显著的变化,包括与其他干预相比的启动持续时间,数量和时间.
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