分子的绿色合成用于治疗被忽视的疾病
João M Anghinoni1, Marina C Dilelio2, Cristiane Y K Shiguemoto3
1Laboratório de Síntese Orgânica Limpa, LASOL, CCQFA, Universidade Federal de Pelotas, UFPel. P.O. Box 354, 96010-900, Pelotas, RS, Brazil.
Current topics in medicinal chemistry
|May 29, 2023
概括
绿色化学方法为被忽视的热带疾病 (NTD) 提供了新型小分子的可持续合成. 本综述强调了治疗莱什曼病,结核病,疟疾和查加斯病的环保方法.
科学领域:
- 绿色化学和可持续合成
- 药物化学和药物发现
- 热带疾病研究研究热带疾病研究
背景情况:
- 忽视的热带疾病 (NTDs) 在全球范围内不成比例地影响贫困人口.
- 传统的活性药物成分 (API) 合成通常涉及污染和能源密集的过程.
- 对于环境友好的方法来开发用于NTDs的新疗法是非常需要的.
结论:
- 绿色化学为开发新型NTD治疗方法提供了可行和可持续的途径.
- 采用环保合成方法对于减少制药生产对环境的影响至关重要.
- 对绿色协议的持续研究将加速急需的NTD治疗方法的发现.
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