周周排泄性血管异常综合体和类似于用内三诺治疗的病变
Nadyr Damasceno1,2, Soraya Horowitz1, Nicolas A Yannuzzi3
1Department of Ophthalmology, Marcilio Dias Navy Hospital, Rio de Janeiro, RJ, Brazil.
European journal of ophthalmology
|May 29, 2023
概括
内三氨有效地治疗了患有周围排泄性血管异常综合体 (PVAC) 和类似病变 (PVAC-RL) 的患者的斑点. 这种治疗改善了视力和减少了视网膜液,为这些罕见疾病提供了负担得起的选择.
科学领域:
- 眼科医生 眼科 眼科
- 视网膜疾病 视网膜疾病
- 血管异常 血管异常
背景情况:
- 周周排泄性血管异常综合体 (PVAC) 和与之相似的病变 (PVAC-RL) 是罕见的,经常被误诊的疾病.
- 这些病变可能导致视力敏度下降,由于相关的黄斑胀.
研究的目的:
- 为了评估内三素在治疗黄斑的疗效.
- 调查PVAC和PVAC-RL的治疗结果,这些治疗结果经常被误诊.
主要方法:
- 一个涉及三名糖尿病患者和一名患有PVAC或PVAC-RL的健康患者的病例系列.
- 患者最初接受了三次内注射aflibercept.
- 随后的治疗包括一次内注射的氨.
主要成果:
- 在triamcinolone注射后,黄斑明显改善,从基线297.5±8.10μm下降到269.2±8.89μm.
- 视力敏度从20/38提高到20/26 (ETDRS尺度).视力敏度从20/38提高到20/26 (ETDRS尺度).视力敏度从20/38提高到20/26 (ETDRS尺度).
结论:
- 内三氨在管理与PVAC和PVAC-RL相关的黄斑胀方面表现出有效性.
- 这项研究表明,氨是一个潜在的有效和负担得起的治疗选择,用于这些罕见的视网膜血管异常与视网膜内液.
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