根据非ST段升高心肌梗塞患者的功能,延迟住院对3年临床结果的影响
Yong Hoon Kim1, Ae-Young Her2, Seung-Woon Rha3
1Division of Cardiology, Department of Inter nal Medicine, Kangwon National University School of Medicine, Chuncheon, Republic of Korea. yhkim02@kangwon.ac.kr.
Cardiology journal
|May 29, 2023
概括
延迟住院没有影响NSTEMI患者的结果. 然而,慢性病显著增加了主要的心脏和脑血管不良事件和死亡率,无论症状到门的时间如何.
科学领域:
- 心脏病学 心脏病学
- 腎臟病學 (nephrology) 是一種醫學專業.
- 临床结果研究研究
背景情况:
- 评估延迟住院 (症状到门的时间 (STD) ≥24小时) 对非ST段升高心肌梗塞 (NSTEMI) 患者的临床结果的影响.
- 根据功能评估结果,特别是慢性病 (CKD) 与非CKD.
研究的目的:
- 确定延迟住院是否会影响新一代药物释放支架 (DES) 治疗NSTEMI患者的3年临床结果.
- 分析功能 (CKD) 对这些结果的影响,与住院时间相关.
主要方法:
- 将4513名NSTEMI患者分为CKD (eGFR < 60mL/min/1.73m2) 和非CKD (eGFR ≥ 60mL/min/1.73m2) 的组.
- 根据延迟住院 (STD ≥24小时) 与早期住院 (STD <24小时) 的患者进行分类.
- 在3年内评估了主要的心脏和脑血管不良事件 (MACCE) 和支架血栓 (ST).
主要成果:
- 多变量和倾向性得分分析显示,在CKD和非CKD组中,有或没有延迟住院的患者的初级和二级结果相似.
- 与非CKD组相比,CKD组的MACCE和死亡率明显高于CKD组,不论是STD.
- 在CKD和非CKD组之间以及在早期和延迟住院组之间,支架血栓发生率是可比的.
结论:
- 慢性病是MACCE和NSTEMI患者死亡率的更重要的预测因素,而不是症状到门的时间.
- 住院时间 (STD) 似乎不是NSTEMI群体中不良结果的主要决定因素.
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