痴呆症中的营养不良和神经精神症状:卡什县痴呆症进展研究
Kaitlyn Kauzor1, Mikaela Drewel1, Hector Gonzalez1
1Department of Psychology, Utah State University, 2810 Old Main Hill, Logan, UT 84321-2810, USA.
International psychogeriatrics
|May 29, 2023
概括
痴呆症患者的营养不良与更严重的神经精神病症状 (NPS) 有关. 针对营养不良的干预措施可能有助于管理痴呆症患者的这些症状.
科学领域:
- 老年学是一门学科.
- 神经科学是一个神经科学.
- 营养科学 营养科学
背景情况:
- 营养状况不佳在痴呆症患者中很常见.
- 营养状况与痴呆症的认知和功能衰退有关.
- 痴呆症中营养和神经精神症状 (NPS) 之间的联系尚不清楚.
研究的目的:
- 在一个基于痴呆症的人口样本中调查营养状况和NPS之间的关联.
- 为了确定营养状况不佳是否预测痴呆症患者NPS的严重程度.
主要方法:
- 在社区中进行了一项纵向的观察性队列研究.
- 292名患有痴呆症的人被跟踪了长达6年的时间.
- 使用修改后的迷你营养评估 (mMNA) 评估营养状况,使用神经精神科目录 (NPI) 评估NPS.
主要成果:
- 营养不良或营养不良的风险人群与营养良好的人群相比,NPI总得分明显高.
- 更好的营养状况 (更高的mMNA得分) 与较低的NPI总得分有关.
- 改善的营养与精神病,抑郁症和冷漠的得分降低相关.
结论:
- 更糟糕的营养状况与痴呆症患者更严重的神经精神症状有显著的关联.
- 旨在预防营养不良的饮食或行为干预措施可能有利于在痴呆患者中管理NPS.
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