多后下鼻轮与较低的喉pH环境有关
Zuzana Javorská1, Karol Zeleník2,3, Kristína Lukáčová1
1Department of Otolaryngology, Head and Neck Surgery, Comenius University, University Hospital, Bratislava, Slovakia.
The Laryngoscope
|May 29, 2023
概括
像木一样的后下鼻 (MPINT) 变化与酸性pH事件有关. 这项研究发现,在患有喉酸性pH值的患者中,MPINT的发生频率更高,这表明存在潜在的因果关系.
科学领域:
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 胃肠病学 胃肠病学
- 鼻科 鼻科是指鼻科的专家.
背景情况:
- 后下鼻 (MPINT) 的像木一样的变化会导致鼻腔阻塞.
- 低pH值的食道外逆流 (EER) 会导致粘膜炎症,可能导致鼻问题.
- 之前的研究没有客观地将酸性pH与MPINT发展联系起来.
研究的目的:
- 调查24小时喉pH值与MPINT存在之间的关联.
- 为了确定喉中的酸性pH环境是否与MPINT形成相关.
主要方法:
- 一项前性病例控制多中心研究,涉及55名慢性EER症状患者.
- 患者填写了反流和鼻腔症状问卷 (RSI®,SNOT-22) 并接受了喉内镜检查 (RFS®).
- 使用24小时口腔喉pH监测来评估酸性pH暴露.
主要成果:
- 在55名患者中有38名 (69%) 患有MPINT.
- 在52.7%的患者中检测到酸性pH值下降.
- 与没有MPINT患者相比,MPINT患者的酸性pH下降 (68.4%) 和增加的酸性暴露指标的流行率显著更高.
结论:
- 通过24小时口腔喉pH监测检测到酸性pH事件的患者中,MPINT明显更常见.
- 这些发现表明,喉中的酸性pH值可能有助于MPINT的形成.
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