在不分化的表现中对儿科急性护理进行机会性腹病查
Karrnan Pathmanandavel1, Melanie Wong1, Emma Williams1
1Department of Allergy and Immunology, The Children's Hospital at Westmead, Sydney, New South Wales, Australia.
Journal of paediatrics and child health
|May 29, 2023
概括
在儿科急诊室进行查心脏病 (CD) 发现0.7%的确诊CD的流行率. 在10岁以上的儿童中测试组织转胺酶IgA可以优化对这种疾病的查.
科学领域:
- 儿科胃肠病学 儿科胃肠病学
- 临床诊断 临床诊断 临床诊断
- 公共卫生查 公共卫生查
背景情况:
- 结肠病 (CD) 通常表现为异型症状,导致诊断延迟.
- 在急诊室 (ED) 进行查,可以确定儿科患者未被诊断的病例.
研究的目的:
- 评估对未分化的儿科患者进行CD查的可行性和收益率.
- 确定CD的患病率,并确定最佳的查策略在这个环境中.
主要方法:
- 从儿科ED患者的血液样本中检测了组织转谷氨酸酶IgA (tTG IgA) 和去胺基质素IgG (DGP IgG) 抗体.
- 积极的结果促使咨询,确认测试,如果需要,胃肠病学转诊.
主要成果:
- 在4.2%的患者中观察到初始阳性抗体结果.
- 活检确认的CD患病率为0.7%,在10岁以上的儿童中患病率更高 (3.3%).
- 诸如家族病史和腹部疼痛等症状等因素与持续的阳性测试有关.
结论:
- 在ED中机会主义的CD查需要进一步调查.
- 在10岁以上的儿童中测试tTG IgA和总IgA可能是最佳的查方法.
- 暂时阳性胆固醇抗体可能会预测未来的CD发展.
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