快速杀死冠状病毒,流感和疹,防止气溶传播
1Department of Basic and Translational Sciences, Penn Dental Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Journal of dental research
|May 29, 2023
概括
低酸 (HOCl) 在牙科喷雾剂中快速破坏空气传播的口腔病毒,如SARS-CoV-2,流感和HSV1. 安全的100 ppm度提供了一种新方法来保护牙科专业人员和患者.
科学领域:
- 传染性疾病 传染性疾病
- 病毒学 病毒学
- 牙科公共卫生 牙科公共卫生
背景情况:
- 牙科手术产生气溶,增加SARS-CoV-2和其他口腔病毒传播风险.
- 目前的表面消毒方法对空气传播和表面传播的病毒是不够的.
- 人们对口服传播的病毒,如流感和单纯疹病毒1 (HSV1) 的认识有所增加.
研究的目的:
- 开发一个实验平台,用于识别在气溶中对口腔病毒的安全和有效的病毒杀毒剂.
- 为了评估低酸 (HOCl) 在摧毁空气传播的口腔病毒中的有效性.
主要方法:
- 一个使用细雾瓶雾化器的实验平台模仿了口服滴水-气溶生成.
- 病毒 (人类贝塔冠状病毒OC43,H1N1流感,HSV1) 混合在气溶中的病毒.
- 暴露时间和低酸 (HOCl) 度进行了测试.
主要成果:
- 100ppm的低酸 (HOCl) 在30秒内完全摧毁了人类β冠状病毒OC43,H1N1流感和HSV1.
- 这种快速杀菌活性发生在原子化器制造的滴滴气溶中.
- 100 ppm的HOCl被认为对人类口腔暴露是安全的.
结论:
- 低酸 (HOCl) 显示出作为一种安全有效的杀毒剂对空气传播的口腔病毒具有显著的潜力.
- 在牙科手术期间,用100ppm的HOCl持续灌可以保护从业人员,工作人员和患者.
- 这种方法提供了一种新的策略,以减轻牙科环境中的病毒传播.
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