中链脂肪酸作为老年人假牙牙炎的替代治疗方法
Ximena Lee Muñoz1,2,3, Cristian Vergara Núñez4, Javiera Jerez Fuentes1
1Institute for Research in Dental Sciences, Faculty of Dentistry, University of Chile, Olivos 943, Independencia, Santiago, Chile.
Clinical oral investigations
|May 29, 2023
概括
中链脂肪酸 (MCFA) 有效地减少了戴着可拆卸假牙的老年人中假牙口炎 (DS) 的症状. 虽然MCFA和赫西丁 (CHX) 都改善了DS,但MCFA在第一周内显示出更快的临床改善.
科学领域:
- 口腔医学是指口腔医学.
- 老年人牙科 老年人牙科
- 菌类学 菌类学是指菌类学.
背景情况:
- 牙口腔炎 (DS) 是一种常见的口腔疾病,影响可拆卸假体 (RP) 佩戴者,通常与Candida物种过度生长有关.
- 目前对DS的治疗方法包括抗真菌药和消毒剂,但为了有效性和可访问性,正在寻找替代方法.
研究的目的:
- 评估中链脂肪酸 (MCFA) 在治疗假牙口腔炎 (DS) 严重性的有效性.
- 为了比较MCFA与赫西丁 (CHX) 对Candida spp.的影响. 在患有DS的老年人 (OP) 中计数.
主要方法:
- 一项随机,受控,三盲研究,涉及43名老年人 (OP) 患有假牙牙炎 (DS).
- 参与者在15天内每天两次接受MCFA或0.12%的化 (CHX) 治疗.
- 临床评估和Candida spp. 的研究. 计数是在基线,7天和15天进行的.
主要成果:
- 治疗MCFA导致了假牙口腔炎 (DS) 临床症状的缓解.
- 虽然这两种治疗都减少了DS的严重程度,但MCFA在一周后显示出改善,而CHX需要两周.
- 在Candida spp. 在研究期内,CHX组的数量在7天后显著下降,但在MCFA组没有显著下降.
结论:
- 中链脂肪酸 (MCFA) 有效地减少了牙套口炎 (DS) 的临床症状,在老年人具有可拆卸假肢 (RP).
- 对于较轻微的DS病例,MCFA提供了一种安全,易于获得和有效的替代治疗方法,特别是管理炎症征兆.
- 无论是MCFA还是CHX,都显示出DS严重程度的显著改善,MCFA提供了更快的临床症状缓解.
相关概念视频
Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy
365
Various diagnostic tests are employed in the diagnostic process for Inflammatory Bowel Disease (IBD), particularly to differentiate between Crohn's disease and ulcerative colitis.
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
365
Chronic Pancreatitis II: Collaborative Care
117
The management of chronic pancreatitis is multifaceted, involving a comprehensive approach that includes thorough assessment, diagnostic testing, and a variety of management strategies.
Assessment:
Assessment:
117
Drugs for Peptic Ulcer Disease: Sucralfate as Mucosal Protective Agents
581
In the intricate landscape of the gastric lumen, excessive acid secretion disrupts the natural defense mechanisms, weakening the mucus-bicarbonate barrier. This vulnerability allows pepsin to infiltrate epithelial cells, digesting mucosal proteins and triggering erosion, leading to ulcer formation.
In this scenario, mucosal protective agents like sucralfate play an essential role. Sucralfate, a complex of sulfated sucrose and aluminum hydroxide, demonstrates its usefulness in acidic conditions,...
In this scenario, mucosal protective agents like sucralfate play an essential role. Sucralfate, a complex of sulfated sucrose and aluminum hydroxide, demonstrates its usefulness in acidic conditions,...
581


