同步高级结肠直肠新生病:临床病理学特征和预后意义
Sahaphol Anannamcharoen1, Piyapan Cheeranont1, Thirayost Nimmanon2
1Department of Surgery Phramongkutklao Hospital, Thailand.
Asian Pacific journal of cancer prevention : APJCP
|May 29, 2023
概括
在结直肠癌 (CRC) 中,同步晚期结直肠瘤 (SCN) 与老年患者和男性占优势有关. 然而,SCN并没有显著影响治疗后的复发率或无病生存率.
科学领域:
- 胃肠病学 胃肠病学
- 手术瘤学手术瘤学
- 在瘤学瘤学.
背景情况:
- 结肠直肠癌 (CRCs) 可以与同步晚期结肠直肠瘤 (SCN) 一起存在.
- 了解SCN在CRC的预后影响对于患者管理至关重要.
研究的目的:
- 为了比较SCN和单独CRC之间的临床病理特征,复发率和无病生存期.
- 为了确定SCN在患有结直肠癌的患者的预后意义.
主要方法:
- 对从CRC患者收集的前性数据的回顾性审查 (2009年1月 - 2014年12月).
- 患者被分为单独的CRC,晚期结直肠腺瘤 (ACA) 的CRC和同步结直肠癌 (S-CRC).
- 对临床病理特征,复发率和接受治疗切除和辅助治疗的患者的无疾病生存率的分析.
主要成果:
- 患有SCN的患者年龄明显大 (p <0.01),SCN在男性 (15.2%) 比女性 (12.3%) (p=0.045) 更常见.
- 在288名治愈切除和辅助治疗的患者中,1年,3年,5年,7年和10年的复发率分别为11.8%,21.2%,24.6%,26.4%和26.7%.
- 无疾病生存率在SCN和单独CRC组之间没有显著差异 (p=0.72).
结论:
- 在CRC中SCN与年龄较大和男性性别有关.
- 治愈切除和完整的辅助治疗导致类似的复发率和没有SCN的CRC的无病生存率.
- 在CRC中,SCN似乎对无病存活率没有显著的负面预后影响.
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