在体积调节弧疗法中,Acuros XB (AXB) 和无otropic分析算法 (AAA) 之间的剂量比较
S Sriram Prasath1,2, Padmanabhan Ramesh Babu2
1Division of Medical Physics, Department of Radiation Oncology, Tata Medical Center, Newtown, Rajarhat, Kolkata, West Bengal, India.
Asian Pacific journal of cancer prevention : APJCP
|May 29, 2023
概括
不同类型分析算法 (AAA) 和Acuros XB (AXB) 剂量计算算法在大多数大电压 (MV) 光子束中显示出极小的差异. 虽然AAA通常计算更高的剂量,但对于平整无波器 (FFF) 束,这些变化在统计上并不显著.
科学领域:
- 医学物理 医学物理
- 辐射瘤学 辐射瘤学
- 放射治疗 物理 物理
背景情况:
- 精确的剂量计算对于有效的放射治疗至关重要.
- 将AAA和AXB等剂量计算算法进行比较对于优化治疗计划至关重要.
- 卷度调制弧线疗法 (VMAT) 需要精确的剂量计算,特别是在异质介质中.
研究的目的:
- 为了比较Anisotropic Analytical Algorithm (AAA) 和Acuros XB (AXB) 的剂量计算精度,用于各种兆电压 (MV) 光子束 (FF和FFF).
- 为了验证这些算法的准确性,在VMAT中使用一个不均的幻影.
- 评估不同幻影材料和目标形状的剂量差异.
主要方法:
- 使用AAA和AXB算法创建的VMAT计划具有单或双弧.
- 一个带有密度校准插头的Cheese Phantom被用于剂量测量.
- 用线性加速器中的电离室测量了点剂量,用于6MV,10MV,6MV FFF和10MV FFF光束.
主要成果:
- 在AAA和AXB之间,PTV结构的最小平均剂量差异为1.2% (p=0.02).
- 在固体水,骨和皮层骨等特定密度插头中观察到显著的剂量差异 (>2%).
- 一般来说,AAA计算的最大和平均剂量高于AXB,除了肺插入外;对于FFF光束来说,差异很小.
结论:
- 对于大多数MV光子束来说,AAA和AXB显示了最小的剂量计算差异,尽管AAA倾向于高估剂量.
- 两种算法的准确性相似,特定组织密度略有差异.
- 建议进一步验证临床实施,特别是对于FFF光束.
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