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酸盐作为全血存储的新型抗凝剂:一项概念验证研究

Maximilian Feth1,2, Robert V Hainline1, Gema Barrera1

  • 1U.S. Army Institute of Surgical Research, JBSA Fort Sam Houston, San Antonio, Texas, USA.

Transfusion
|May 29, 2023
PubMed
概括

酸盐显示出作为血液抗凝剂的潜力,但需要进一步的研究来解决储存期间的血小板损失. 这项研究探讨了酸-酸-氨酸-乳糖 (PPDA-1) 作为酸-氨酸-乳糖 (CPDA-1) 的替代品.

关键词:
这是一种抗凝血药物.血液的储存 储存血液的储存酸是一种酸.血小板 血小板 是酸铁酸盐的使用方法输血是输血的方法之一.

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Hemostasis is a crucial process that prevents excessive blood loss from damaged blood vessels. It involves various mechanisms such as vasoconstriction, platelet adhesion and activation, and fibrin formation. The importance of each mechanism depends on the type of vessel injury. In contrast, thrombosis is the abnormal formation of a blood clot within the blood vessels, leading to potential complications if the clot obstructs blood flow. Thrombosis can be caused by increased coagulability of the...
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