埃克斯基因和氧化还原稳态
Elisa Félix-Soriano1, Kristin I Stanford2
1Dorothy M. Davis Heart and Lung Research Institute, The Ohio State University Wexner Medical Center, Columbus, OH, USA; Department of Physiology and Cell Biology, The Ohio State University College of Medicine, Columbus, OH, USA.
Redox biology
|May 29, 2023
概括
运动生理学研究突出了运动激素,信号分子,调解运动的好处. 本综述探讨了exerkines如何与氧化还原生物学相互作用,以改善健康和运动适应性.
科学领域:
- 运动生理学 运动生理学
- 转毒生物学 转毒生物学
- 分子生物学分子生物学
背景情况:
- 运动生理学研究正在扩大,原因是发现了称为运动因子的循环因子.
- 运动期间分泌的exerkines调节其全身和组织特异性的作用.
- 虽然已知exerkines的代谢作用,但它们对氧化还原信号的影响越来越被认可.
研究的目的:
- 审查当前关于氧化还原生物学和exerkine作用之间的相互作用的证据.
- 阐明埃克斯基因在调节氧化还原稳定和细胞应激反应中的作用.
- 为了突出表达在炼适应过程中炼素的意义,涉及氧化还原信号.
主要方法:
- 对调查exerkines和氧化还原生物学研究的文献综述.
- 对炼期间的exerkine分泌和功能研究的分析.
- 综合有关exerkine介导的氧化还原信号通路的发现.
主要成果:
- 埃克斯基因在调节氧化还原信号和恒温中起着至关重要的作用.
- 它们调解了身体对氧化应激的反应,改善了健康结果.
- 通过整合氧化还原信号,exerkines有助于运动适应.
结论:
- 炼是关键的调解者,将炼与改善健康和应激弹性联系起来.
- 炼和氧化还原生物学之间的交叉对话对炼生理学至关重要.
- 准exerkine-redox相互作用为治疗疾病提供了潜在的治疗干预措施.
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