在急性胰腺炎中出院后死亡率的详细特征
Dóra Czapári1, Alex Váradi2, Nelli Farkas3
1Institute for Translational Medicine, Medical School, University of Pécs, Pécs, Hungary; Center for Translational Medicine, Semmelweis University, Budapest, Hungary.
Gastroenterology
|May 29, 2023
概括
在急性胰腺炎 (AP) 后出院的患者面临着显著更高的死亡风险,几乎是住院死亡的两倍,特别是在90天内. 年龄,并发症和入院标志物预测了这种增加的风险.
科学领域:
- 胃肠病学和肝病学
- 临界护理医学 临界护理医学
- 流行病学 流行病学
背景情况:
- 急性胰腺炎 (AP) 的住院生存率很高 (95-98%).
- 下院后的发病率和 AP 后的死亡率是令人担忧的.
- 了解AP后死亡率对于患者的治疗结果至关重要.
研究的目的:
- 调查急性胰腺炎分泌后死亡的风险,原因和预测因素.
- 为了比较出院后的死亡率与住院死亡率.
- 确定影响出院后早期和晚期死亡的关键因素.
主要方法:
- 在2012年至2021年期间,来自25个中心的2613名患者被跟踪.
- 一般和医院人口作为对照.
- 多变量分析确定了死亡率的独立风险因素.
主要成果:
- 出院后的死亡率是普通人群的三倍.
- 第一年出院后的死亡率 (5.5%) 几乎是住院死亡率 (3.5%) 的两倍.
- 年龄,并发症,肌素,葡萄糖和肺液预测死亡率;原因包括心力衰竭,败血症,缓冲症和感染.
结论:
- 在出院后的90天内,几乎与住院期间同样多的患者死亡.
- 术后护理应包括心血管评估,并发症监测和瘤护理.
- 未来的AP研究需要至少90天的出院后的随访.
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