在异常发病性内高血压的分流手术后,光盘血管密度的变化
Nermien Salah El-Dien Mohammed El-Haddad1, Shymaa Adel Ismael2, Adel Abd El-Wahab2
1Faculty of Medicine, Al-Azhar University, Egypt; Faculty of Medicine, Armed Force Medicine Collage, Egypt.
Photodiagnosis and photodynamic therapy
|May 29, 2023
概括
光盘血管密度在转移手术后在异常性内高血压患者显著下降. 这种变化显示出作为大脑脊髓液压力降低的生物标志物的潜力.
科学领域:
- 眼科医生 眼科 眼科
- 神经学 神经学
- 医疗成像医学成像
背景情况:
- 自发性内高血压 (Idiopathic intracranial hypertension,IIH) 是一种由内血压升高而表现出来的疾病.
- 乳头发疹是脑内压力增加的标志,会影响视盘.
- 穿手术是一种常见的治疗方法,用于降低IIH患者的内压力.
研究的目的:
- 为了研究光盘血管密度的变化,在转移手术后的IIH患者.
- 评估光盘血管密度作为大脑脊髓液 (CSF) 压力降低的潜在生物标志物.
主要方法:
- 光学连贯断层扫描血管造影 (OCT-A) 用于测量光盘血管密度.
- 在21名IIH患者的分流手术前和后两个月进行了测量.
- 进行了眼科和神经学检查,以及腰部穿刺以测量CSF压力.
主要成果:
- 在手术后,光盘血管密度在各个区域 (整体图像,内盘,周囊,上层,下层) 显著下降.
- 这种减少在微血管 (毛细血管) 和宏血管 (所有血管) 两方面都被观察到.
- 手术前的CSF打开压力与手术前的血管密度和手术后的血管密度减少正相关.
结论:
- 在IIH患者中,分流手术导致光盘血管密度显著下降.
- 光盘血管密度作为可靠的生物标志物,用于监测手术后CSF开口压力的降低.
更多相关视频
07:18Evaluation of Capillary and Other Vessel Contribution to Macular Perfusion Density Measured with Optical Coherence Tomography Angiography
Published on: February 18, 2022
1.8K
08:55Translaminar Autonomous System Model for the Modulation of Intraocular and Intracranial Pressure in Human Donor Posterior Segments
Published on: April 24, 2020
3.1K
相关概念视频
01:25Glaucoma: Overview
636
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
636
01:27Open Angle Glaucoma: Treatment
497
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Drugs such as carbonic anhydrase inhibitors, α2- and...
497