迷幻药物:治疗革命的门
D J Heal1, S L Smith2, S J Belouin3
1DevelRx Ltd, BioCity, Nottingham, NG1 1GF, UK; Department of Life Sciences, University of Bath, Bath, BA2 7AY, UK.
Neuropharmacology
|May 29, 2023
概括
最近的研究表明,在迷幻药物领域取得了显著的进展,特别是 псилоцибин和MDMA. 这些化合物在治疗抑郁症和创伤后应激障碍等疾病方面表现有前途,朝着主流治疗用途迈进.
科学领域:
- 神经药理学神经药理学
- 精神病学是一个精神病学.
- 临床心理学 临床心理学
背景情况:
- 自2018年以来,迷幻药物研究领域已取得重大进展.
- 美国国立卫生研究院 (NIH) 召开了一系列关于西的研讨会,召集了领先的专家.
- 包括全球视角,补充基于美国的研究.
研究的目的:
- 提供关于迷幻研究进展的全面更新.
- 弥合基础科学和潜在的主流疗法之间的差距.
- 讨论迷幻药物的发展对全球的影响.
主要方法:
- 综述了近期基本和临床迷幻药物研究的进展.
- 来自全球领先专家参加的一系列研讨会的见解.
- 包括全球贡献和专家评价.
主要成果:
- 美国食品和药物管理局 (FDA) 已经授予了 псилоцибин (TRD,MDD) 和MDMA (PTSD) 的突破性治疗名称.
- 临床试验正在进行中,针对各种指示,包括抑郁症,焦虑症,PTSD和物质使用障碍.
- 迷幻药正在被用于各种疾病,包括与癌症相关的痛苦和慢性疼痛.
结论:
- 像psilocybin和MDMA这样的迷幻化合物证明了各种心理健康和神经疾病的治疗潜力.
- 目前正在进行的临床试验和监管方面的进展表明,向主流治疗应用过渡.
- 国际兴趣和研究工作预计将在潜在的FDA批准后增加.
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