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澳大利亚儿童器官捐献,2000-2019:2009年国家改革计划的影响. 一个基于人口的注册数据研究
Tal T Klein1, Michael J O'Leary2, Lukas Staub3
1Children's Hospital at Westmead, Sydney, NSW.
The Medical journal of Australia
|May 29, 2023
概括
2009年国家改革计划没有增加澳大利亚16岁以下儿童的器官捐献率. 对成年捐献者的更广泛的策略可能无法有效地改善儿科器官捐献人数.
科学领域:
- 公共卫生 公共卫生
- 儿科医学 儿科医学
- 移植科学 移植科学
背景情况:
- 2009年国家改革计划旨在提高澳大利亚的器官捐献率.
- 评估该计划对儿科器官捐献者的具体影响对于有针对性的干预至关重要.
研究的目的:
- 评估澳大利亚2009年国家改革计划对16岁以下已故器官捐赠者的有效性.
- 分析改革后儿科器官捐献者的数量和特征的变化.
主要方法:
- 追溯观察时间序列研究.
- 分析澳大利亚和新西兰器官捐献 (ANZOD) 注册数据 (2000-2019).
- 捐赠者率 (每百万人口) 的比较 (2000-2008年) 之前和改革后 (2009-2019年) 捐赠者年龄为16岁以下和16岁以上.
主要成果:
- 在2000年至2019年期间,发现了400名16岁以下潜在的已故器官捐赠者 (374名实际捐赠者).
- 16岁以下儿童的年捐献率中位数为每百万人口中3.3 (改革前) 和4.2 (改革后) (IRR为1.15,不显著).
- 16岁以上的捐献者比例显著增加 (IRR为1.75). 捐赠者的特征 (年龄,体重) 仍然相似.
结论:
- 2009年国家改革计划没有显著增加16岁以下儿童的器官捐献率.
- 一般的改革举措可能不足以增强儿科器官捐赠.
- 有针对性的策略可能是必要的,以改善儿童器官捐赠者的器官捐赠.
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