肥胖是整个生命中对新陈代谢和精神健康的类风险状态
Michael Leutner1, Elma Dervic2,3, Luise Bellach1
1Department of Internal Medicine III, Clinical Division of Endocrinology and Metabolism, Medical University of Vienna, Waehringer Guertel 18-20, A-1090, Vienna, Austria.
Translational psychiatry
|May 29, 2023
概括
肥胖明显增加了许多精神疾病的风险,包括抑郁症和焦虑症. 这种关联在年轻人和女性中更为明显,突出显示了肥胖患者心理健康查的必要性.
科学领域:
- 公共卫生 公共卫生
- 精神病学是一个精神病学.
- 代谢障碍 代谢障碍 代谢障碍
背景情况:
- 肥胖是一种普遍的代谢障碍,与心理健康问题有关.
- 肥胖患者面临精神病共同诊断的风险增加.
- 生物途径和临床观察证据支持肥胖与心理健康的联系.
研究的目的:
- 研究肥胖诊断与广泛的精神疾病之间的关联.
- 分析肥胖和心理健康诊断之间的时间关系.
- 确定影响这些关联的人口因素,如年龄和性别.
主要方法:
- 分析奥地利国家登记数据 (1997-2014) 对于住院服务.
- 包括肥胖的医院诊断 (ICD-10:E66) 和ICD-10精神疾病的3级.
- 应用Cochran-Mantel-Haenszel方法和时间顺序比率进行统计分析,分年龄几十年分层.
主要成果:
- 肥胖诊断显著提高了抑郁症,精神病谱,焦虑,饮食和人格障碍的几率 (pcorr <0.01,或> 1.5).
- 肥胖通常在精神疾病之前被诊断出来,除了精神病谱系障碍.
- 观察到显著的性别差异,女性患大多数疾病的风险更高,但不包括精神分裂症和尼古丁成.
结论:
- 肥胖是所有年龄段严重心理健康障碍的重要前体.
- 肥胖的精神病共同诊断的风险在年轻人和女性中特别高.
- 对于被诊断患有肥胖症的患者来说,例行心理健康查至关重要,以使早期干预和治疗成为可能.
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