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Updated: Jul 28, 2025

Methods for the Discovery of Novel Compounds Modulating a Gamma-Aminobutyric Acid Receptor Type A Neurotransmission
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Published on: August 16, 2018

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化学蛋白质组学揭示了微生物群衍生的GPRC5A的芳香性单胺激素激应剂

Xiaohui Zhao1, Kathryn R Stein1, Victor Chen2

  • 1Department of Immunology and Microbiology, Scripps Research, La Jolla, CA, USA.

Nature chemical biology
|May 29, 2023
PubMed
概括

研究人员确定了肠道微生物如何产生与宿主蛋白相互作用的内醇代谢物. 他们发现芳香单胺激活GPRC5A受体,为新的治疗策略铺平了道路.

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