呼吸衰竭重症儿童的营养不良和60天死亡率:一个前性队列研究
Sina Amirjani1, Narjes Ahmadizadeh2, Azita Behzad2
1Department of Clinical Nutrition and Dietetics, Faculty of Nutrition and Food Technology, National Nutrition and Food Technology Research Institute, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
BMC pediatrics
|May 29, 2023
概括
患有急性呼吸衰竭的儿童营养不良显著增加了60天死亡的风险. 营养不良在儿科重症监护病房中很常见,并影响生存率.
科学领域:
- 儿科重症监护医药 儿科重症监护医药
- 营养科学 营养科学
- 呼吸系统药物 呼吸系统药物
背景情况:
- 急性呼吸衰竭是儿童的危急情况.
- 营养不良是重症儿童常见的并发症.
- 营养不良对儿科急性呼吸衰竭死亡率的影响需要调查.
研究的目的:
- 研究患有急性呼吸衰竭的儿科患者营养不良和60天死亡率之间的关联.
- 确定与死亡风险增加相关的特定营养参数.
主要方法:
- 研究了一组126名患有急性呼吸衰竭的儿童 (2个月至13岁).
- 在入院时,使用Z-score (BMI,身高相对年龄,体重相对年龄,体重相对身高) 评估营养状况.
- 60天死亡率是主要结局,使用考克斯回归分析.
主要成果:
- 根据各种Z分数,41-50%的患者营养不良.
- 整体60天死亡率为27.8%.
- 营养不良,特别是基于体重与年龄,BMI与年龄和体重与身高的Z分数,与60天死亡率的增加显著相关.
结论:
- 在儿童重症监护病房的机械通风儿童中,营养不良很普遍.
- 营养不良是儿科急性呼吸衰竭60天死亡的一个重要风险因素.
- 早期营养评估和干预对于改善结果至关重要.
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