胺与埃托米达用于创伤患者的快速序列输管:韩国一级创伤中心的一项回顾性研究

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Jinjoo Kim¹, Kyoungwon Jung¹, Jonghwan Moon¹

¹Division of Trauma Surgery, Department of Surgery, Ajou University School of Medicine, Suwon, Republic of Korea.

BMC emergency medicine

|May 29, 2023

概括

胺和埃托米达通常用于创伤患者的快速序列输管 (RSI). 这项研究发现胺和埃托米达的结果没有显著差异,尽管胺使用与更大的血液动力学不稳定性有关.

科学领域:

紧急医疗紧急医疗
麻醉学麻醉学
创伤护理创伤护理

背景情况:

快速序列输管 (RSI) 是创伤患者呼吸道管理的一个关键程序.
胺和埃托米达是经常用于RSI的镇静剂,但它们在创伤中的比较有效性仍在争论中.
由于缺乏共识,需要进行比较创伤复苏中这些药物的研究.

研究的目的:

为了比较胺与埃托米达对第一通成功的效果以及在接受紧急输管治疗的创伤患者的患者结果.
在创伤复苏的背景下评估胺和埃托米达的安全性和有效性.

主要方法:

追溯对944名受创患者进行内管道输入术的回顾.
使用倾向性得分匹配对胺和埃托米达特组之间的结果进行比较.
分析了第一通成功率,死亡率,ICU停留时间,呼吸机日和住院时间.

主要成果:

包括620名患者;118人接受了胺,502人接受了埃托米达.
胺组显示出更大的血液动力学不稳定性 (更快的心率,更低血压) 和更高的伤害严重性得分.
两组之间没有观察到第一通成功率,死亡率,ICU/住院长度或呼吸机日的显著差异.

结论:

与埃托米达相比,在遭受RSI的创伤患者中服用胺与血液动力学不稳定性增加有关.
尽管有血动力学差异,但胺和埃托米达在第一通成功和整体患者情绪方面表现出相似的临床结果.
在创伤中治疗RSI的胺和埃托米达的选择可能取决于患者特定的因素和机构协议,因为结果似乎相似.

关键词:

埃托米酸是一种胺基氨酸 (ketamine) 是一种可以快速序列输入管道的输入.复苏复苏复苏复苏复苏创伤是一个创伤.

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