预期审计和反抗菌药物管理计划对卡巴胺消费的影响:一项准实验性研究 (IPANEMA研究)
Mar Ronda1, Ariadna Padullés2,3, Imma Grau1,4,5
1Infectious Disease Department, Hospital Universitari de Bellvitge-Idibell, Hospitalet de Llobregat, Barcelona, Spain.
The Journal of antimicrobial chemotherapy
|May 30, 2023
概括
使用电子工具进行前性审计和反 (PAF) 有效地减少了泌尿器科的卡巴胺使用. 这种抗微生物管理干预措施没有对患者安全结果产生负面影响.
科学领域:
- 传染性疾病 传染性疾病
- 抗微生物药物管理委员会
- 医疗信息学 医疗信息学
背景情况:
- 碳烯耐药性是一个日益增长的全球健康威胁.
- 抗生素管理计划对于优化抗生素使用至关重要.
- 电子工具可以提高管理干预的效率.
研究的目的:
- 评估前性审计和反 (PAF) 干预措施与电子工具相结合对碳烯利用的影响.
- 评估这种干预措施对患者结果和安全的影响.
- 为了确定这种方法在大学医院的泌尿病科的有效性.
主要方法:
- 一个准实验性的研究设计,比较预干预和干预时期.
- 在抗菌药物管理计划中实施PAF干预,与电子工具集成.
- 通过DDD/100患者日 (PD) 和DOT/100PD测量卡巴胺的使用;评估患者安全结果.
主要成果:
- 碳烯使用量下降了9% (DDD/100 PD) 和13% (DOT/100 PD).
- 总体而言,抗生素使用也显著降低了DDD/100 PD (3%) 和DOT/100 PD (7%).
- 患者安全指标,包括感染率和住院时间,保持稳定,证明了干预的安全性.
结论:
- 联合PAF和电子工具的干预有效地减少了卡巴胺的消耗.
- 这种策略是安全的,不会影响患者的治疗结果.
- 这种方法代表了一种有价值的工具,用于减少广谱抗生素使用的抗菌药物管理工作.
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