参与减肥临床试验的动机
Alyssa Susanto1, Nicholas R Fuller1, Samantha Hocking1,2
1Boden Group, Central Clinical School, Faculty of Medicine and Health, Charles Perkins Centre, The University of Sydney, Camperdown, New South Wales, Australia.
Clinical obesity
|May 30, 2023
概括
男人参与减肥试验的比例较低. 这项研究发现,男性参加健康咨询,而女性受到家庭和外表的激励,这表明量身定制的招聘可以促进男性参与.
科学领域:
- 临床试验 临床试验
- 健康心理学 心理健康心理学
- 肥胖问题研究研究
背景情况:
- 在减肥临床试验中,男性的代表性明显不足,通常不到25%的参与者.
- 了解参与者的动机对于改善试验招募和有效性至关重要.
研究的目的:
- 调查参与减肥试验的个体的动机.
- 确定这些动机是否存在性别特异的差异.
- 为提高男性参与未来试验的策略提供信息.
主要方法:
- 体重减轻试验参与者的注册表被用来招募24个人 (9名男性,15名女性).
- 进行了半结构面试 (20分钟),以探索人们的期望和动机.
- 采访被录音,转录,并使用NVivo软件进行主题分析.
主要成果:
- 改善健康是男性和女性减肥的普遍动机.
- 男性参与的原因往往是医疗保健专业人士的建议,以预防与肥胖相关的并发病.
- 妇女的参与受到家庭和美学因素的显著影响,例如服装和时尚.
结论:
- 参与减肥试验存在性别特定的动机.
- 根据确定的性别差异定制招聘策略可能会增加男性入学率.
- 解决这些动机差异是提高临床试验代表性的关键.
相关概念视频
01:11Clinical Trials: Overview
3.1K
Clinical development focuses on how the drug will interact with the human body and encompasses four key phases of clinical trials, each serving a specific purpose in assessing the safety and effectiveness of new drugs. These phases overlap and build upon one another. Phase I involves a small group of healthy volunteers (typically 20-80 individuals) or, in cases where significant toxicity is expected, patients with the targeted disease, such as cancer or AIDS. The volunteers are tested for...
3.1K
01:16Clinical Trials
6.9K
Clinical trials are prospective experimental studies conducted on humans to determine the safety and efficacy of treatments, drugs, diet methods, and medical devices. Using statistics in clinical trials enables researchers to derive reasonable and accurate conclusions from the collected data, allowing them to make wise decisions in uncertain situations. In medical research, statistical methods are crucial for preventing errors and bias.
There are four phases in a clinical trial. A phase one...
There are four phases in a clinical trial. A phase one...
6.9K
01:23Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches
150
Biopharmaceutical studies constitute a vital field aiming to enhance drug delivery methods and refine therapeutic approaches, drawing upon diverse interdisciplinary knowledge. In research methodologies, the choice between controlled and non-controlled studies significantly influences the study's reliability and accuracy.
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast,...
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast,...
150
01:24Obesity
552
The Body Mass Index (BMI) is a numerical value derived from a person's weight and height, used to categorize individuals into weight ranges. It is calculated using the formula: weight in kilograms divided by height in meters squared. Obesity is a health condition characterized by excessive accumulation of adipose tissue that poses health risks, often diagnosed with a BMI ≥ 30. This excess fat storage occurs when surplus dietary calories are converted into triglycerides and stored in...
552
01:20Study Designs in Epidemiology
292
Epidemiological study designs are fundamental tools for investigating the distribution, determinants, and control of health conditions in populations. They help researchers understand the relationships between exposures and outcomes, and they broadly fall into two categories: "observational" and "experimental" studies.
Observational studies are those where the researcher does not intervene but rather observes natural variations. They include cross-sectional, cohort, and...
Observational studies are those where the researcher does not intervene but rather observes natural variations. They include cross-sectional, cohort, and...
292
01:11Blinding
2.5K
Blinding is a commonly used method of not telling participants which treatment a subject is receiving. Blinding is a critical part of a randomized control trial or RCT. It reduces the bias that affects the results. In an RCT, blinding is used in the form of a placebo. A placebo effect occurs when untreated subjects falsely believe they have received the treatment and report improved symptoms. A placebo or a dummy treatment is administered to subjects to negate the bias caused by such an effect.
2.5K