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Updated: Jul 28, 2025

CRISPR/Cas9 Editing of the C. elegans rbm-3.2 Gene using the dpy-10 Co-CRISPR Screening Marker and Assembled Ribonucleoprotein Complexes.
07:46

CRISPR/Cas9 Editing of the C. elegans rbm-3.2 Gene using the dpy-10 Co-CRISPR Screening Marker and Assembled Ribonucleoprotein Complexes.

Published on: December 11, 2020

5.9K

HNRNPH1通过毒素外子排除来调节神经保护性冷震蛋白RBM3的表达

Julie Qiaojin Lin1,2, Deepak Khuperkar1,2, Sofia Pavlou1,3

  • 1UK Dementia Research Institute and Department of Clinical Neurosciences, University of Cambridge, Cambridge Biomedical Campus, Cambridge, UK.

The EMBO journal
|May 30, 2023
PubMed
概括

低温通过通过剪接因子HNRNPH1.1增加RNA结合动机3 (RBM3) 来增强神经保护. 这种机制涉及抑制毒素外子,为神经保护提供新的治疗点.

关键词:
这是一个CRISPR屏幕.这是一个RBM3RBM3RBM3替代性拼接是一种替代性的拼接.抗寒性蛋白质是一种抗寒性蛋白质.毒物 毒物 毒物 毒物 毒物

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