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对于花生过敏儿童的花生值与饮食成分有关

Daisy Luiten¹, Maarten Biezeveld¹, Olga van Doorn¹

¹Department of Paediatrics, OLVG Hospital, Amsterdam, The Netherlands.

Immunity, inflammation and disease

|May 30, 2023

概括

饮食成分会影响儿童的花生过敏值. 特定的营养摄入量与值水平相关,这表明饮食在花生敏感性变异性中起作用.

科学领域:

过敏和免疫学过敏和免疫学
营养科学营养科学
微生物组研究微生物组研究

背景情况:

花生过敏在受影响儿童的值水平中表现出显著的变化.
饮食成分对肠道屏障功能和微生物群的影响表明,在这个值变化中可能发挥作用.

研究的目的:

调查营养摄入量,肠道微生物组成和花生过敏儿童的花生值水平之间的关联.

主要方法:

涉及口服食品挑战的横截面研究,以确定花生值水平.
对营养和食物摄入量进行3天食物日记的分析.
评估便和唾液微生物组成的分子技术.
使用多变量线性和逻辑回归的统计分析.

主要成果:

在较高的碳水化合物和维生素A摄入量与增加的花生值水平之间观察到积极的关联.
发现与更高摄入长链多不和脂肪酸,氨酸和omega-6脂肪酸的负面关联.
值水平与便/唾液微生物组成之间没有直接关联,但在具有积极挑战的儿童中,微生物特征 (蛋白质细菌,细菌菌) 发生了变化.

结论:

饮食成分代表了一种与过敏儿童花生值水平相关的新奇因素.
特定的营养素可能会调节对花生过敏原的免疫反应,影响临床反应性.

关键词:

饮食饮食饮食饮食微生物组是一个微生物组.口服食物挑战口服食物挑战对于花生过敏的过敏门值是指一个值.

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