活在艾滋病毒感染者的患者在数量上摄入不够的食物
Bárbara Ferreira Vercesi1, Izabela Spereta Moscardini2, Gabriel Perri Esteves3
1Universidade de São Paulo, Faculdade de Medicina de Ribeirão Preto, Departamento de Clínica Médica, Ribeirão Preto, SP, Brasil, bavercesi@gmail.com.
Archives of endocrinology and metabolism
|May 30, 2023
概括
长期接受高强度抗逆转录病毒疗法 (HAART) 的艾滋病毒感染者 (PLWH) 显示能量摄入量增加,但营养仍然不足. 这有助于心血管疾病的风险,尽管类似的休息能量消耗,无论HAART的持续时间.
科学领域:
- 营养科学 营养科学
- 艾滋病毒/艾滋病研究研究
- 代谢健康 代谢健康
背景情况:
- 艾滋病毒感染者 (PLWH) 经常面临代谢并发症和营养挑战.
- 高强度抗逆转录病毒疗法 (HAART) 对于治疗艾滋病毒至关重要,但可能影响营养状况.
- 了解HAART持续时间,能量消耗和营养摄入之间的相互作用对于患者护理至关重要.
研究的目的:
- 为了估计PLWH中的能源支出.
- 为了将估计的能源消耗与通常的食物消耗进行比较.
- 研究HAART持续时间对营养摄入量和充足性的影响.
主要方法:
- 休息能量支出 (REE) 估计使用人体测量和生物电阻分析 (BIA) 与梅尔乔尔方程.
- 饮食参考摄入量 (DRI) 和24小时回忆用于评估报告的食物摄入量与营养建议的一致性.
- 在61个PLWH中分析人体测量数据,BIA和饮食摄入量.
主要成果:
- 患者表现出糖尿病 (24.5%),高血压 (54%) 和脂质失调 (90.1%) 的高患病率.
- 随着HAART持续时间超过10年 (533kcals),能量摄入量增加,但没有满足能源需求.
- 休息能量支出 (REE) 在不同的HAART持续时间中保持相似.
结论:
- 现有的PLWH具有异构代谢特征和不充分的饮食模式.
- 类似的REE,无论HAART持续时间如何,都会加剧心血管疾病的风险.
- 营养支持和监测对于在HAART上的PLWH至关重要.
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