治疗性抑制CXCR1/2:我们的情况如何?

Sebastian Sitaru1,2, Agnes Budke1, Riccardo Bertini3

  • 1Institute of Cardiovascular Physiology and Pathophysiology, Walter Brendel Center of Experimental Medicine, University Hospital, Ludwig-Maximilian University, Großhaderner Str. 9, Planegg-Martinsried, 82152, Munich, Germany.

概括

中性粒细胞中的CXCL8-CXCR1/2轴对炎症性疾病和癌症至关重要. 抑制这种途径对胃肠道疾病有希望,但需要对感染进行仔细评估.