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Updated: Jul 28, 2025

Parallel Interrogation of β-Arrestin2 Recruitment for Ligand Screening on a GPCR-Wide Scale using PRESTO-Tango Assay
09:03

Parallel Interrogation of β-Arrestin2 Recruitment for Ligand Screening on a GPCR-Wide Scale using PRESTO-Tango Assay

Published on: March 10, 2020

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用户定义的配体的基于结构的GPCR计算优化:对生物传感器的开发的影响.

Lorenzo Di Rienzo1, Mattia Miotto1, Edoardo Milanetti2,1

  • 1Center for Life Nano- & Neuro-Science, Istituto Italiano di Tecnologia, Viale Regina Elena 291, 00161 Rome, Italy.

Computational and structural biotechnology journal
|May 30, 2023
PubMed
概括

这项研究引入了一种计算方法,通过修改本地Ste2受体来设计酵母生物传感器,以识别像上腺素这样的新配体. 这种方法使得定制生物传感器的开发能够在没有对特定受体或G蛋白的预先了解的情况下实现.

关键词:
生物传感器生物传感器在GPCR中,GPCR是指GPCR.蛋白质工程是一种蛋白质工程.

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