在一个新的乙烯基菌的热力学生命极限时强制自
Evgenii N Frolov1, Alexander G Elcheninov1, Alexandra V Gololobova1
1Federal Research Center of Biotechnology, Winogradsky Institute of Microbiology, Russian Academy of Sciences, Moscow, Russia.
Frontiers in microbiology
|May 30, 2023
概括
研究人员发现了第一个有义务自的乙酸性细菌,Aceticella autotrophica. 这一发现促进了对生命和微生物能量代谢的热力学极限的理解,特别是在低能量的环境中.
科学领域:
- 生物能源学 生物能源学
- 微生物学 微生物学
- 进化生物学 进化生物学
背景情况:
- 了解生命的热力学极限至关重要,因为生命的热力学极限是非常重要的.
- 能量生物量子是指能量的生物量子.
- 仍然没有定义.
- 能够在低能量的基板上生存的乙基性 prokaryotes 作为最小能量产量的模型.
- 已知的乙原体是自主养的,这限制了对义务自养的洞察力.
研究的目的:
- 描述了第一个有义务自的乙基细菌.
- 为了研究这种新生物体的遗传学和代谢特征.
- 了解使乙原体有义务自的进化适应.
主要方法:
- 一种新型乙原菌的分离和表征, *Aceticella autotrophica* gen. nov., sp. 的新型乙原菌. 新型,菌株3443-3AcT. 这种菌株的
- 遗传学分析将新属置于Thermoanaerobacterium,Thermoanaerobacter和Caldanaerobacter (TTC) 组中的一个.
- 对*A. autotrophica*和相关物种如*Thermoanaerobacter kivui*进行比较基因组和代谢分析.
主要成果:
- *Aceticella autotrophica* 3443-3AcT被确定为第一个有义务自的乙原体.
- 在遗传学上, *A. autotrophica* 属于TTC 群体,与可选性自营菌 *Thermoanaerobacter kivui* 共享 acetogenic 特性.
- *A. autotrophica*的独特代谢机制,包括缺乏糖运输系统,支持其强制性自,与其他TTC成员形成鲜明对比.
结论:
- 发现*A. autotrophica*扩大了已知的乙烯基细菌的多样性,并为研究强制性自身养提供了一个模型.
- *A. autotrophica*和*T. kivui*都使用能量转化酶 (Ech-acetogens),并且可能是垂直遗传的乙酸生成.
- 不同的进化路径,包括横向的基因转移,塑造了这些相关物种的独特的乙烯基机械和代谢能力.
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