糖尿病作为尼日利亚人中风的危险因素:系统性审查和元分析
Taoreed Adegoke Azeez1, Ibikunle Moses Durotoluwa2, Akintomiwa Ibrahim Makanjuola3
1Department of Medicine, Reddington Multi-Specialist Hospital, Lagos, Nigeria.
糖尿病是尼日利亚中风的重要危险因素. 在中风中糖尿病的可归因风险很高,在全国范围内增加,特别是在南部地区.
科学领域:
- 神经学 神经学
- 内分泌学 在内分泌学.
- 公共卫生 公共卫生
背景情况:
- 脑卒中是尼日利亚普遍存在的疾病.
- 糖尿病是一种已知的中风可修改的风险因素.
- 关于尼日利亚中风患者糖尿病的发生频率的国家数据有限.
研究的目的:
- 估计尼日利亚糖尿病作为中风风险因素的程度.
- 量化尼日利亚中风患者糖尿病的可归因风险.
主要方法:
- 根据PRISMA指南进行了系统审查.
- 在非洲杂志在线 (AJOL),PubMed,SCOPUS和谷歌学者中进行文学搜索.
- 使用DerSimonian Laird随机效应模型进行元分析,通过纽卡斯尔-太华尺度进行质量评估,并使用I2统计数据进行异质性分析.
主要成果:
- 在全国分布的研究中,共有9397名患者被纳入.
- 中风患者的加权平均年龄为53.7岁.
- 尼日利亚患者中风中糖尿病的可归因风险为0.20 (95% CI:0.17-0.22; p < 0.0001),表明有重大贡献.
结论:
- 糖尿病在尼日利亚人口中具有很高的中风风险.
- 这种风险在不同地区不均,尼日利亚南部风险明显较高.
- 人们观察到,糖尿病中风风险在全国范围内逐渐增加,特别是在2000年以来.
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