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C9ORF72可以抑制JAK-STAT介导的炎症

Weilun Pang1, Fenghua Hu1

  • 1Department of Molecular Biology and Genetics, Weill Institute for Cell and Molecular Biology, Cornell University, Ithaca, NY 14853, USA.

iScience
|May 30, 2023
PubMed
概括

失去C9ORF72会通过激活JAK-STAT通路和STING引起炎症. 雅克抑制剂可以治疗这些炎症反应在肌缩侧面硬化症和前叶退化.

关键词:
细胞生物学 细胞生物学豁免权是一种豁免权.分子生物学分子生物学

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