持续的嗅觉功能障碍与长期COVID患者的睡眠质量低下和焦虑有关
Alna Carolina Mendes Paranhos1,2, Apio Ricardo Nazareth Dias1, Thalita da Rocha Bastos1
1Health and Biological Science Center, State University of Pará, Pará, Brazil.
Frontiers in neuroscience
|May 30, 2023
概括
长期COVID患者的睡眠质量差与焦虑和嗅觉障碍有关. 了解这些联系对于管理长期COVID神经症状和改善患者护理至关重要.
科学领域:
- 神经学 神经学
- 睡眠医学 睡眠医学
- 传染性疾病 传染性疾病
背景情况:
- 睡眠质量差是长期COVID患者中普遍存在的问题.
- 神经症状经常与长期的COVID一起发生,影响患者的福祉.
- 识别睡眠质量差的特征和关联对于有效的长期COVID管理至关重要.
研究的目的:
- 描述长期COVID患者睡眠质量差的社会人口统计和临床特征.
- 研究睡眠质量差和其他神经症状,包括焦虑,认知障碍和嗅觉障碍之间的关系.
- 分析长期COVID队列中睡眠质量差的流行率和关联.
主要方法:
- 一项涉及巴西288名长期COVID患者,自我报告的神经症状的横截面研究.
- 标准化协议用于评估,包括匹兹堡睡眠质量指数 (PSQI) 和贝克焦虑库存.
- 数据收集发生在2020年11月至2022年10月期间,有131名患者接受了详细评估.
主要成果:
- 睡眠质量差在女性 (76.3%) 较为常见,平均年龄为44.04岁.
- 焦虑和嗅觉障碍在睡眠质量差的患者中明显更为普遍.
- 多变量分析证实,焦虑和嗅觉功能障碍与长期COVID的睡眠质量差有关.
结论:
- 睡眠质量差是长期COVID的重要神经症状,通常与焦虑和嗅觉功能障碍同时发生.
- 这些发现强调需要将睡眠质量评估纳入长期COVID患者的临床管理.
- 对这些关联的神经生物学基础的进一步研究可能会揭示新的治疗点.
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