对接受关节整形手术的艾滋病毒/艾滋病患者住院并发症的分析 - 一个倾向匹配的队列研究
Ashish R Chowdary1, Vishaal Sakthivelnathan2, Jack Beale3
1University of Texas Southwestern Medical Center, Dallas, TX, USA.
Journal of clinical orthopaedics and trauma
|May 30, 2023
概括
关节整形术 (THA) 是人类免疫缺陷病毒 (HIV) 患者的安全手术. 艾滋病毒阳性和艾滋病毒阴性患者的术后并发症率相似,艾滋病毒队列中的输血率较低.
科学领域:
- 整形外科手术 整形外科手术
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
背景情况:
- 患有人类免疫缺陷病毒 (HIV) 的患者面临由于骨代谢失调和药物副作用而增加的骨科风险.
- 关节整形术 (THA) 的发生率在HIV阳性个体中正在上升.
- 鉴于手术技术和艾滋病毒管理的进步,最新的研究对于评估艾滋病毒患者的THA结果至关重要.
研究的目的:
- 评估和比较THA在艾滋病毒感染和没有艾滋病毒感染的患者的术后结果.
- 为了确定这些队列之间的并发症率和康复率的潜在差异.
主要方法:
- 利用国家数据库分析THA结果.
- 使用倾向算法将艾滋病毒阳性患者与艾滋病毒阴性对照组匹配.
- 在匹配组之间比较人口统计数据和术后并发症率.
主要成果:
- 与未匹配的HIV阴性队列相比,HIV队列更年轻,糖尿病和肥胖率更低.
- 在没有匹配的分析中,艾滋病毒患者的急性损伤,肺炎,周围假肢感染和伤口脱光率更高.
- 在匹配分析中,艾滋病毒患者的输血率明显较低 (5.0%与8.3%相比). 肺炎,伤口衰变和手术部位感染的发病率在统计上没有差异.
结论:
- 关节整形手术显示,艾滋病毒阳性和艾滋病毒阴性患者的术后并发症率相似.
- 接受THA治疗的HIV阳性患者经历了较低的输血率.
- 这些发现表明,THA对于艾滋病毒感染者来说是一种安全有效的程序.
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