Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Cell Specific Gene Expression01:58

Cell Specific Gene Expression

13.6K
Multicellular organisms contain a variety of structurally and functionally distinct cell types, but the DNA in all the cells originated from the same parent cells. The differences in the cells can be attributed to the differential gene expression. Liver cells, whose functions include detoxification of blood, production of bile to metabolize fats, and synthesis of proteins essential for metabolism, must express a specific set of genes to perform their functions. Gene expression also varies with...
13.6K
What is Gene Expression?01:42

What is Gene Expression?

168.5K
Overview
Gene expression is the process in which DNA directs the synthesis of functional products, that is, proteins. Cells can regulate gene expression at various stages. It allows organisms to generate different cell types and enables cells to adapt to internal and external factors.
Genetic Information Flows from DNA to RNA to Protein
A gene is a stretch of DNA that serves as the blueprint for functional RNAs and proteins. Since DNA is made up of nucleotides and proteins consist of amino...
168.5K

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Understanding the link between PMN-MDSCs and CXCL8-CXCR1/2 axis in primary myelofibrosis.

Frontiers in cell and developmental biology·2026
Same author

From global to local: comparing the EAT-Lancet planetary health diets with the traditional Mediterranean Diet across Mediterranean countries.

International journal of food sciences and nutrition·2026
Same author

Reproducibility and Validity of a Nova-Based Food Frequency Questionnaire in Older Italian Adults: The NFFQ-Elderly.

Nutrients·2026
Same author

Movement behaviors, psychosocial well-being and childhood obesity: the IDEFICS/I.Family cohort.

International journal of obesity (2005)·2026
Same author

Modeling pediatric low-grade glioma heterogeneity using human forebrain organoids.

Molecular cancer·2026
Same author

Nicotinamide N-Methyl Transferase (NNMT) Sustains Innate Sensitivity to NAMPT Inhibition in YAP-dependent Stem-like/Mesenchymal Prostate Cancer.

International journal of biological sciences·2026

相关实验视频

Updated: Jul 28, 2025

Single-cell Gene Expression Profiling Using FACS and qPCR with Internal Standards
10:50

Single-cell Gene Expression Profiling Using FACS and qPCR with Internal Standards

Published on: February 25, 2017

16.6K

通过expressyouRcell可视化基因表达在时间,空间和单细胞中的变化.

Martina Paganin1, Toma Tebaldi2,3, Fabio Lauria1

  • 1Institute of Biophysics, CNR Unit Trento, Trento, Italy.

iScience
|May 30, 2023
PubMed
概括

新的R包expressyouRcell简化了复杂的基因表达和蛋白质数据的可视化. 它将多维变化转化为动态的细胞图形图,以更好地理解和沟通.

关键词:
计算生物信息学是指计算机生物信息学.

更多相关视频

A Combinatorial Single-cell Approach to Characterize the Molecular and Immunophenotypic Heterogeneity of Human Stem and Progenitor Populations
09:34

A Combinatorial Single-cell Approach to Characterize the Molecular and Immunophenotypic Heterogeneity of Human Stem and Progenitor Populations

Published on: October 25, 2018

6.7K
Droplet Barcoding-Based Single Cell Transcriptomics of Adult Mammalian Tissues
10:12

Droplet Barcoding-Based Single Cell Transcriptomics of Adult Mammalian Tissues

Published on: January 10, 2019

18.6K

相关实验视频

Last Updated: Jul 28, 2025

Single-cell Gene Expression Profiling Using FACS and qPCR with Internal Standards
10:50

Single-cell Gene Expression Profiling Using FACS and qPCR with Internal Standards

Published on: February 25, 2017

16.6K
A Combinatorial Single-cell Approach to Characterize the Molecular and Immunophenotypic Heterogeneity of Human Stem and Progenitor Populations
09:34

A Combinatorial Single-cell Approach to Characterize the Molecular and Immunophenotypic Heterogeneity of Human Stem and Progenitor Populations

Published on: October 25, 2018

6.7K
Droplet Barcoding-Based Single Cell Transcriptomics of Adult Mammalian Tissues
10:12

Droplet Barcoding-Based Single Cell Transcriptomics of Adult Mammalian Tissues

Published on: January 10, 2019

18.6K

科学领域:

  • 生物信息学是一种生物信息学.
  • 计算生物学 计算生物学
  • 基因组学就是基因组学.

背景情况:

  • 高通量技术产生复杂的基因表达数据集.
  • 大量的数据和复杂的实验设计阻碍了结果的解释和沟通.

研究的目的:

  • 介绍 expressyouRcell,一个用于可视化多维基因和蛋白质表达变化的 R 包.
  • 通过动态图形简化复杂的生物数据的理解和沟通.

主要方法:

  • 开发了expressyouRcell R包的开发工作.
  • 基因和蛋白质表达的可视化使用动态细胞图片.
  • 适用于单细胞,大量RNA测序 (RNA-seq) 和蛋白质组学数据集.

主要成果:

  • expressyouRcell有效地映射了转录和蛋白质水平的多维变化.
  • 该软件包可生成动态的图形图表,对单元类型主题地图进行表示.
  • 在各种高通量数据集中展示了灵活性和可用性.

结论:

  • expressyouRcell提高了复杂的基因表达数据的解释和通信.
  • 该工具在视觉上降低了复杂性,帮助研究人员了解动态细胞变化.
  • 改进了生物大数据的标准定量解释.