胆囊壁厚度作为食道的非侵入性标记:系统性审查和元分析
Anas Elgenidy1, Ahmed M Afifi2, Prasun K Jalal2
1Cairo University, Cairo, Egypt.
Journal of clinical and experimental hepatology
|May 30, 2023
概括
通过超声波测量胆囊壁厚度 (GBWT) 是一种有希望的,非侵入性的工具,用于检测慢性肝病患者的食道静脉 (EV). 这种方法有助于早期诊断,可能避免昂贵和危险的内镜手术.
科学领域:
- 肝病学 肝病学是一种肝病学.
- 诊断成像 诊断成像 诊断成像
- 胃肠病学 胃肠病学
背景情况:
- 早期检测食道静脉 (EV) 对于管理慢性肝病 (CLD) 至关重要.
- 由于成本和潜在的并发症,非侵入性诊断方法优先于内镜.
- 胆囊壁厚度 (GBWT) 可能受到门高血压的影响,这是EV发展的关键因素.
研究的目的:
- 评估超声波测量GBWT的诊断和预测实用性,用于识别患有CLD的患者的EV.
主要方法:
- 在PubMed,Scopus,Web of Science和Embase上进行了系统的文献搜索,截至2022年3月15日.
- 这些关键词包括"","",和"胆囊".
- 使用R软件和meta-disc进行了元分析和诊断测试准确性 (DTA).
主要成果:
- 包括12项包括1343名参与者的研究.
- 在EV患者中观察到显著更大的GBWT (MD = 1.86毫米).
- DTA分析得出AUC为86%,Q*为0.80,聚合灵敏度为73%,特异性为86%.
结论:
- 超声波测量GBWT显示显著的希望作为一个非侵入性预测器的食道静脉在CLD患者.
- GBWT可以作为一个有价值的查工具,可能指导进一步的诊断决策.
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