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Updated: Jul 28, 2025

Paramyxoviruses for Tumor-targeted Immunomodulation: Design and Evaluation Ex Vivo
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创新的重新定位的瘤性疹病毒对抗nectin4阳性癌症

Andrea Vannini1,2, Federico Parenti1, Cristina Forghieri1

  • 1Department of Medical and Surgical Sciences (DIMEC), University of Bologna, Bologna, Italy.

Frontiers in molecular biosciences
|May 30, 2023
PubMed
概括

一种新型的瘤免疫治疗性疹病毒,R-421,专门针对表达Nectin4的癌细胞,不影响正常细胞. 这种工程病毒在预临床模型中显示出降低瘤生长和提高免疫治疗疗效的前景.

关键词:
抗癌疫苗 抗癌疫苗 抗癌疫苗免疫疗法 免疫疗法尼克丁4的使用方法型疹简单疹病毒科性病毒病毒.胰腺癌,胰腺癌.重定位重定位重新定位三重阴性乳腺癌是什么

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