在神经血管疾病的内血管治疗后,全身麻醉和对比诱导的脑病变之间存在关联
Zhihong Zhong1, Hongyang Ni1, Jun Zhu1
1Department of Neurosurgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Frontiers in neurology
|May 30, 2023
概括
全身麻醉可能会增加对比诱导脑病变 (CIE) 的风险,这是内血管手术后罕见的神经并发症. 这项研究发现,全身麻醉和CIE发生之间存在显著的相关性.
科学领域:
- 神经学 神经学
- 麻醉学 麻醉学
- 放射学 放射学是一门学科.
背景情况:
- 对比诱导脑病变 (CIE) 是一种罕见的神经并发症,发生在内血管手术后.
- 对于CIE的危险因素尚未完全理解,特别是麻醉的作用.
研究的目的:
- 调查接受内血管治疗的患者中CIE的发生率.
- 为了确定全身麻醉与局部麻醉相比,是否是CIE的风险因素.
主要方法:
- 对接受内血管治疗的1,043名患者的回顾性审查 (2018年6月至2021年6月).
- 分析使用倾向得分匹配和后勤回归来评估麻醉和CIE之间的关联.
- 程序包括动脉瘤栓塞,支架植入和血栓切除术.
主要成果:
- 共有14名患者 (1.34%的发病率) 患有CIE.
- 在64.5%的患者中使用全身麻醉,在35.5%的患者中使用局部麻醉.
- 在倾向性得分匹配后,在全身麻醉和增加CIE风险 (P=0.007) 之间发现了显著的关联.
结论:
- 全身麻醉可能是对比诱导脑病变的危险因素.
- 普罗波,一种常见的麻醉剂,可能与增加CIE发生有关.
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