在蔬菜种植者中甲状腺功能的决定因素,主要暴露于pyrifos:印度尼西亚中央爪的一个横截面研究
Jen Fuk Liem1,2, Imam Subekti3, Muchtaruddin Mansyur4
1Department of Occupational Health and Safety, Faculty of Medicine and Health Sciences, Universitas Kristen Krida Wacana, Kota Jakarta Barat, DKI Jakarta, Indonesia.
Heliyon
|May 30, 2023
概括
职业接触农药,特别是pyrifos,影响了印尼农民的甲状腺功能. 较高的甲状腺刺激激素 (TSH) 水平与增加的暴露和特定生物标志物相关,表明甲状腺功能障碍的风险.
科学领域:
- 环境健康 环境健康
- 内分泌学 在内分泌学.
- 职业医学 职业医学是专业的.
背景情况:
- 职业接触农药,特别是pyrifos (CPF),是甲状腺功能障碍的潜在危险因素.
- 了解农业工人甲状腺功能的特定决定因素对于公共卫生至关重要.
研究的目的:
- 评估影响印尼蔬菜种植者甲状腺刺激激素 (TSH) 水平的因素,主要暴露于pyrifos (CPF).
主要方法:
- 一项涉及151名蔬菜农户的研究评估了社会人口统计和职业数据.
- 估计了累积暴露水平 (CEL),并测量了血清TSH,甲状腺蛋白 (Tg),自由甲状腺素 (FT4) 和尿液分泌量 (UIE).
- 统计分析包括曼·惠特尼U测试和多重线性回归来确定TSH决定因素.
主要成果:
- 较高的TSH度与较高的Tg/FT4比率,高的CEL和较低的UEE或FT4水平有关.
- 中位数TSH为1.46 mIU/L,FT4为1.17 ng/dL.
结论:
- 证实了像CPF这样的农药的甲状腺破坏性,Tg/FT4比率,CEL,FT4,UIE和喷后的日子被确定为TSH决定因素.
- 这些发现凸显了农业人口暴露在农药中的甲状腺疾病风险.
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