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儿童癌症化疗全球价格的变化:描述性分析

Catherine Habashy¹, Tatenda T Yemeke², Nancy S Bolous³

¹Division of Pediatric Hematology-Oncology, University of North Carolina, Chapel Hill, NC, USA.

EClinicalMedicine

|May 30, 2023

概括

化疗价格在全球范围内差异很大,高收入国家为必要的儿科癌症药物支付的费用要高得多. 这些数据可以为全球价格谈判提供信息,并改善癌症儿童的获取.

科学领域:

全球健康全球健康
儿科瘤学儿科瘤学
卫生经济学卫生经济学

背景情况:

儿童癌症的全球生存率显示出明显的差异,特别影响低收入和中等收入国家.
关于化疗定价的有限信息阻碍了对必要药物的知情预算和价格谈判.
扩大化疗接入是解决儿科癌症生存差距的全球优先事项.

研究的目的:

为了生成个人化疗剂和常见儿童癌症治疗方案的比较真实世界的价格数据.
提供关键的定价信息,以支持预算决策和政府和利益相关者的价格谈判.
为改善资源有限的环境中改善化疗接入的策略提供信息.

主要方法:

来自世界卫生组织 (WHO) 儿童必需药物清单 (EMLc) 和全球儿童癌症倡议 (GICC) 的精选化疗剂优先安排.
利用了IQVIA MIDAS数据和健康管理科学 (MSH) 公共数据,用于化疗价格和采购量 (2012-2019).
汇总和比较世卫组织各地区和世界银行 (WB) 收入分类中的化疗价格.

主要成果:

分析了代表97个国家的约11亿剂量数据,按世界银行收入水平 (HIC,UMIC,LLMIC) 分类.
高收入国家 (HICs) 的药物价格中位数是中高收入国家 (UMICs) 的0.9-20.4倍,低收入和中低收入国家 (LLMICs) 的0.9-15.5倍.
在HIC中,治疗方案通常更昂贵,对于血液性恶性瘤,非适应方案和更高风险分层.

结论:

这项研究提供了迄今为止对儿童癌症全球化疗剂价格的最广泛的分析.
这些发现为未来的儿科瘤学成本效益分析提供了基础.
这些数据应指导政府和利益相关者在药物价格谈判和开发聚合采购策略方面,以提高全球获得儿童癌症治疗的机会.

关键词:

基本的药物基本的药物全球儿童健康儿童健康卫生经济学卫生经济学卫生政策卫生政策儿科瘤学儿科瘤学

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