口腔内镜肌肉切除术对食道分泌器的有效性和安全性
Elise M Wessels1, Jeroen M Schuitenmaker1, Barbara A J Bastiaansen1
1Amsterdam University Medical Centres, Gastroenterology & Hepatology, Amsterdam, Netherlands.
Endoscopy international open
|May 30, 2023
概括
口腔内镜肌切除术 (POEM) 提供了一种有效和安全的治疗表性分泌管,显著减少食道症状. 这种微创手术在患有食道运动障碍的患者中显示出有希望的结果.
科学领域:
- 胃肠病学 胃肠病学
- 最少侵入性的手术
- 食道运动障碍 食道运动障碍
背景情况:
- 腹分泌器是罕见的食道外囊,经常与潜在的食道运动障碍有关.
- 目前的手术治疗 (带有肌肉切除的分泌器切除术) 具有显著的不良事件率.
- 需要为这些患者提供更安全,更有效的治疗选择.
研究的目的:
- 评估口腔内镜肌切除术 (POEM) 治疗食道分泌器的疗效和安全性.
- 评估POEM对患有潜在运动障碍的患者食道症状的影响.
主要方法:
- 对17名患有食道分泌器的患者进行了回顾性队列研究,这些患者接受了POEM (2014年10月 - 2022年12月).
- 通过医疗记录和电话调查收集的数据.
- 主要结局:治疗成功定义为Eckardt分数<4 (≥2分减少).
主要成果:
- 治疗成功率为68.8%.
- 埃卡特得分的中位数显著下降,从7到1 (p < 0.001).
- 平均分泌器尺寸从3.6厘米减少到2.9厘米 (p < 0.001);不良事件发生在11.8%的患者中.
结论:
- 口腔内镜肌切除术 (POEM) 是食道分泌管的有效和安全的治疗选择.
- 在患有潜在食道运动障碍的患者中,POEM显示出显著的症状减轻和解剖改善.
- 这种手术与不良事件和短期住院率较低有关.
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