混合牙病变:一个罕见实体的病例系列
Muhammad Raza1, Arsalan Ahmed1, Jamshid Abdul-Ghafar2
1Department of Pathology and Laboratory Medicine, Aga Khan University Hospital, Karachi, Pakistan.
Heliyon
|May 30, 2023
概括
混合性牙病变,罕见且难以诊断,在年轻女性中经常以骨化纤维瘤或水泥骨化纤维瘤的形式出现. 保守的外科治疗通常是有效的,没有观察到复发.
科学领域:
- 口腔和面病理学 口腔和面病理学
- 牙发生性瘤 牙发生性瘤
- 手术病理学手术病理学
背景情况:
- 混合牙病变是一种罕见的实体,具有多个不同的组织学组成部分.
- 它们的复杂性质给临床医生和病理学家带来了重大诊断挑战.
- 了解它们的特征对于准确的诊断和有效的管理至关重要.
研究的目的:
- 调查混合牙病变的临床,放射和病理特征.
- 分析这些罕见病变的行为和治疗结果.
- 提高对混合牙病变的认识,提高诊断准确度.
主要方法:
- 对2012年至2020年间诊断的混合性牙病变的血素和氨酸染色幻灯片的回顾性审查.
- 从患者病历中收集人口统计和放射学数据.
- 对临床表现,放射学发现,组织学类型和治疗方式的分析.
主要成果:
- 确定了8例病例,主要影响年轻人 (平均年龄为19.1岁),女性倾向 (1:1.7比).
- 部病变更为常见,呈现为胀与相关症状,如出血和疼痛. 从放射学上看,病变大多是有界线的,放射性.
- 最常见的组织学组成部分是骨化纤维瘤/骨化纤维瘤 (62%),其次是巨细胞颗粒瘤样病变 (25%).
结论:
- 混合性牙病变最常发生在年轻的女性在他们的第二个十年,经常涉及骨化纤维瘤和水泥-骨化纤维瘤组件.
- 手术管理,包括核切除和切割,似乎充足,在随访期间没有报告复发.
- 对于这些罕见的病变,建议采取保守的治疗方法.
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