卵巢癌向治疗的社会人口学差异在全国样本中的卵巢癌
Saber A Amin1,2, Lindsay J Collin3, Juraj Kavecansky4
1Cancer Epidemiology and Health Outcomes, Rutgers Cancer Institute of New Jersey, New Brunswick, NJ, United States.
Frontiers in oncology
|May 30, 2023
概括
向治疗越来越多地用于一线卵巢癌治疗. 然而,存在差异,非西班牙裔黑人女性接受这些先进治疗的可能性较低,这凸显了平等获取的必要性.
科学领域:
- 在瘤学瘤学.
- 临床研究 临床研究
- 健康差异 在健康上的差异
背景情况:
- 晚期卵巢癌的治疗随着向疗法的整合而发展.
- 了解影响这些新型治疗方法在一线护理中的使用因素至关重要.
研究的目的:
- 研究与使用向疗法在卵巢癌的初始治疗相关的人口和临床因素.
- 确定卵巢癌患者获得一线向治疗的潜在差异.
主要方法:
- 从国家癌症数据库分析2012年至2019年期间被诊断为I-IV期卵巢癌的患者的数据.
- 使用描述性统计和后勤回归来评估患者特征与接受向治疗之间的关联.
主要成果:
- 在99,286名患者中,4.1%接受了向治疗. 与非西班牙裔白人女性相比,非西班牙裔黑人女性接受向治疗的可能性较低 (OR=0.87).
- 接受新辅助化疗的患者更有可能接受向治疗 (OR=1.26). 大约28%的向治疗接受者接受了新辅助疗法.
- 接受向治疗的情况因年龄,阶段,并发症,保险状况和社区教育水平而异.
结论:
- 根据患者人口统计学,临床因素和医疗保健准入指标,观察到针对性治疗接收的显著差异.
- 新辅助药物向治疗的高比例引发了人们对手术时间和治疗结果的潜在影响的担忧.
- 需要对综合治疗数据进行进一步的研究,才能充分理解这些发现的含义.
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