全景体积临床手持式光声和超声波成像
Changyeop Lee1, Seonghee Cho1, Donghyun Lee1
1Departments of Electrical Engineering, Convergence IT Engineering, Mechanical Engineering, and Medical Science and Engineering, Medical Device Innovation Center, Pohang University of Science and Technology, Pohang 37673, Republic of Korea.
Photoacoustics
|May 30, 2023
概括
这项研究引入了一个新的手持式全景体积光声学 (PA) 和超声波 (US) 成像系统. 该系统可实现血管网络的详细3D可视化和量化以及体内氧气和.
科学领域:
- 生物医学工程 生物医学工程
- 医疗成像医学成像
- 在光学成像系统中,光学成像
背景情况:
- 光声学成像 (PA) 提供了与临床超声波 (US) 结合的结构和功能信息.
- 目前的2D PA/US成像在很大程度上依赖于操作员的技能,强调了需要改进的3D成像解决方案.
- 开发先进的成像系统对于提高各种医学领域的诊断能力至关重要.
研究的目的:
- 开发和评估一种新的手持全景体积临床光声学和超声波成像系统.
- 评估系统对大视野成像和血管网络定量分析的能力.
- 证明该系统在体内临床应用和功能参数量化方面的潜力.
主要方法:
- 一个手持式600g扫描仪 (70 × 62 × 110 mm3) 已被开发用于全景体积PA/US成像.
- 获得多个PA/US扫描并与手动6DOF校正进行马赛克拼接,用于大视野重建.
- 进行了最大振幅投影图像的在线可视化和光谱未混合数据的离线定量化.
主要成果:
- 该系统成功地对人类手臂 (FOV: 331 × 38 mm2) 和子 (FOV: 129 × 120 mm2) 的血管网络进行了全景成像.
- 在主要动脉和静脉 (辐射动脉,手臂动脉,动脉,关节) 中量化了血红蛋白氧和水平.
- 幻影实验验证了系统的性能和成像能力.
结论:
- 开发的手持式全景体积PA/US系统为大规模3D血管成像提供了强大的平台.
- 该系统能够对功能参数进行定量评估,例如体内血红蛋白氧和度等.
- 这项技术在心血管成像,皮肤病学,血管外科和瘤学等领域具有显著的临床应用潜力.
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